Triprolidine


Triprolidine
Triprolidine
Systematic (IUPAC) name
2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-
prop-1-enyl]pyridine
Clinical data
AHFS/Drugs.com monograph
Pregnancy cat. C (US)
Legal status OTC (US)
Routes Oral
Pharmacokinetic data
Bioavailability 4% oral
Protein binding 90%
Metabolism Hepatic (CYP2D6)
Half-life 4-6 hours
Excretion Renal
Identifiers
CAS number 486-12-4 YesY
ATC code R06AX07
PubChem CID 5282443
DrugBank DB00427
ChemSpider 4445597 YesY
UNII 2L8T9S52QM YesY
KEGG D01782 N
ChEMBL CHEMBL855 YesY
Chemical data
Formula C19H22N2 
Mol. mass 278.391 g/mol
SMILES eMolecules & PubChem
Physical data
Melt. point 60 °C (140 °F)
Solubility in water 500 mg/mL (20 °C)
 N(what is this?)  (verify)

Triprolidine (Actidil, Myidil) is an over-the-counter antihistamine with anticholinergic properties. It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms. Like many over-the-counter antihistamines, the most common side effect is drowsiness. Triprolidine is a quick acting drug that can clear congestion and stop runny noses in 15-30 minutes.[citation needed]

References