3F8 is a murine, IgG3cite journal |author=Kushner BH, Cheung NK |title=GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma |journal=Blood |volume=73 |issue=7 |pages=1936–41 |year=1989 |pmid=2653466 |doi= |url=http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=2653466] monoclonal antibody which binds to GD2.cite web |url=http://www.mskcc.org/mskcc/html/3215.cfm#261335 |title=Sloan-Kettering - Neuroblastoma: 3F8 Monoclonal Antibody Therapy Q & A |accessdate=2008-02-19 |format= |work=]

It has been used in the detection and treatment of neuroblastoma. [cite web |url=http://www.cancer.org/docroot/NWS/content/NWS_1_1x_New_Drug_Targets_Tough_Childhood_Cancer.asp |title=ACS :: New Drug Targets Tough
Childhood Cancer |accessdate=2008-02-19 |format= |work=
] <cite journal |author=Yeh SD, Larson SM, Burch L, "et al" |title=Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities |journal=J. Nucl. Med. |volume=32 |issue=5 |pages=769–76 |year=1991 |pmid=1902508 |doi= |url=http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=1902508] cite journal |author=Dauer LT, St Germain J, Williamson MJ, "et al" |title=Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma |journal=Health Phys |volume=92 |issue=1 |pages=33–9 |year=2007 |pmid=17164597 |doi=10.1097/01.HP.0000231583.32904.6c |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00004032-200701000-00005]

ee also

* Monoclonal antibody therapy


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • 3F8 — A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory produced substances that can locate and bind to cancer cells …   English dictionary of cancer terms

  • Global warming controversy — refers to a variety of disputes, significantly more pronounced in the popular media than in the scientific literature,[1][2] regarding the nature, causes, and consequences of global warming. The disputed issues involve the causes of increased… …   Wikipedia

  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • IBM 1130 — The IBM 1130 Computing System was introduced in 1965. It was IBM s least expensive computer to date, and was aimed at price sensitive, computing intensive technical markets like education and engineering. The IBM 1800 was a process control… …   Wikipedia

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • Cetuximab — ? Monoclonal antibody Type Whole antibody Source Chimeric (mouse/human) Target EGF receptor Clinical data AHFS/Drugs.com …   Wikipedia

  • Neuroblastoma — Neuroblastoma, NOS Classification and external resources microscopic view of a typical neuroblastoma with rosette formation ICD 10 C …   Wikipedia

  • GD2 — is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans. The relatively… …   Wikipedia

  • Gemtuzumab ozogamicin — ? Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target CD33 Clinical data Trade names Mylotarg AHFS/ …   Wikipedia

  • Oregovomab — ? Monoclonal antibody Type Whole antibody Source Mouse Target CA125 Clinical data Pregnancy cat.  ? Legal status  ? …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.