3F8

3F8 is a murine, IgG3cite journal |author=Kushner BH, Cheung NK |title=GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma |journal=Blood |volume=73 |issue=7 |pages=1936–41 |year=1989 |pmid=2653466 |doi= |url=http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=2653466] monoclonal antibody which binds to GD2.cite web |url=http://www.mskcc.org/mskcc/html/3215.cfm#261335 |title=Sloan-Kettering - Neuroblastoma: 3F8 Monoclonal Antibody Therapy Q & A |accessdate=2008-02-19 |format= |work=]

It has been used in the detection and treatment of neuroblastoma. [cite web |url=http://www.cancer.org/docroot/NWS/content/NWS_1_1x_New_Drug_Targets_Tough_Childhood_Cancer.asp |title=ACS :: New Drug Targets Tough
Childhood Cancer |accessdate=2008-02-19 |format= |work=
] <cite journal |author=Yeh SD, Larson SM, Burch L, "et al" |title=Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities |journal=J. Nucl. Med. |volume=32 |issue=5 |pages=769–76 |year=1991 |pmid=1902508 |doi= |url=http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=1902508] cite journal |author=Dauer LT, St Germain J, Williamson MJ, "et al" |title=Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma |journal=Health Phys |volume=92 |issue=1 |pages=33–9 |year=2007 |pmid=17164597 |doi=10.1097/01.HP.0000231583.32904.6c |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00004032-200701000-00005]

ee also

* Monoclonal antibody therapy

References


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