CA7

Carbonic anhydrase VII, also known as CA7, is a human gene.cite web | title = Entrez Gene: CA7 carbonic anhydrase VII| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=766| accessdate = ]

PBB_Summary
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summary_text = Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.cite web | title = Entrez Gene: CA7 carbonic anhydrase VII| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=766| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sly WS, Hu PY |title=Human carbonic anhydrases and carbonic anhydrase deficiencies. |journal=Annu. Rev. Biochem. |volume=64 |issue= |pages= 375–401 |year= 1995 |pmid= 7574487 |doi= 10.1146/annurev.bi.64.070195.002111
*cite journal | author=Breton S |title=The cellular physiology of carbonic anhydrases. |journal=JOP |volume=2 |issue= 4 Suppl |pages= 159–64 |year= 2002 |pmid= 11875253 |doi=
*cite journal | author=Rivera C, Voipio J, Kaila K |title=Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII. |journal=J. Physiol. (Lond.) |volume=562 |issue= Pt 1 |pages= 27–36 |year= 2005 |pmid= 15528236 |doi= 10.1113/jphysiol.2004.077495
*cite journal | author=Montgomery JC, Venta PJ, Eddy RL, "et al." |title=Characterization of the human gene for a newly discovered carbonic anhydrase, CA VII, and its localization to chromosome 16. |journal=Genomics |volume=11 |issue= 4 |pages= 835–48 |year= 1992 |pmid= 1783392 |doi=
*cite journal | author=Loftus BJ, Kim UJ, Sneddon VP, "et al." |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295–308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927
*cite journal | author=Chagnon P, Michaud J, Mitchell G, "et al." |title=A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis. |journal=Am. J. Hum. Genet. |volume=71 |issue= 6 |pages= 1443–9 |year= 2003 |pmid= 12417987 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Vullo D, Voipio J, Innocenti A, "et al." |title=Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |journal=Bioorg. Med. Chem. Lett. |volume=15 |issue= 4 |pages= 971–6 |year= 2005 |pmid= 15686895 |doi= 10.1016/j.bmcl.2004.12.052

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