OTU domain containing 4
Symbols OTUD4; DKFZp434I0721; DUBA6; HIN1; HSHIN1; KIAA1046
External IDs OMIM611744 MGI1098801 HomoloGene35370 GeneCards: OTUD4 Gene
RNA expression pattern
PBB GE OTUD4 203479 s at tn.png
PBB GE OTUD4 203480 s at tn.png
PBB GE OTUD4 220669 at tn.png
More reference expression data
Species Human Mouse
Entrez 54726 73945
Ensembl ENSG00000164164 ENSMUSG00000036990
UniProt Q01804 n/a
RefSeq (mRNA) NM_001102653.1 NM_001081164.1
RefSeq (protein) NP_001096123.1 NP_001074633.1
Location (UCSC) Chr 4:
146.03 – 146.1 Mb
Chr 8:
82.16 – 82.2 Mb
PubMed search [1] [2]

OTU domain-containing protein 4 is a protein that in humans is encoded by the OTUD4 gene.[1][2][3]

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells.[3]


  1. ^ Raineri I, Senn HP (Feb 1993). "HIV-1 promotor insertion revealed by selective detection of chimeric provirus-host gene transcripts". Nucleic Acids Res 20 (23): 6261–6. doi:10.1093/nar/20.23.6261. PMC 334514. PMID 1475186. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=334514. 
  2. ^ Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K (May 2003). "Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors". Cancer Res 63 (9): 2024–7. PMID 12727813. 
  3. ^ a b "Entrez Gene: OTUD4 OTU domain containing 4". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54726. 

Further reading

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