Ethcathinone

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IUPAC_name = 2-ethylamino-1-phenyl-propan-1-one

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CAS_number = 51553-17-4
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DrugBank =
C=13|H=15|N=1|O=1
molecular_weight = 177.3
bioavailability =
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routes_of_administration = oral, intranasal

Ethcathinone (also called Ethylpropion, N-ethylcathinone and 2-ethylaminopropiophenone), is a stimulant drug. It is an active metabolite of diethylcathinone and has a stimulant effect on the CNS. Ethcathinone has recently been reported as having been sold as "ecstasy" in the Australian city of Cairns, along with 4-Methylmethcathinone. [ [http://www.cairns.com.au/article/2008/06/18/4685_local-news.html Killer pills hit Cairns] ] [ [http://www.abc.net.au/news/stories/2008/06/17/2277735.htm Police warn of potentially fatal 'fake ecstasy'] ]

Pharmacology

Ethcathinone is a methylphenidate-like DA/NE reuptake inhibitor (Rothman 2005). Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine. Chemically, it is the "N"-ethyl homologue of cathinone and dimethylcathinone.

ide effects

;Severe
*Insomnia
*Pulmonary hypertension
*Stroke
*Psychosis

;Cardiovascular
*Tachycardia, hypertension, arrhythmia, chest pain

;Ear, nose, and throat
*Xerostomia, metallic taste

;Endocrine
*Changes in libido, gynecomastia, menstrual irregularities

;Eye
*Blurred vision

;Gastrointestinal
*Nausea/vomiting, constipation, abdominal cramps

;Hematological
*Bone marrow depression, agranulocytosis, leukopenia

;Neurological
*Tremor

;Psychological
*Euphoria, agitation, nervousness, restlessness, dizziness, anxiety, headache, mental depression, seizures

;Skin
*Rash, hives, alopecia, ecchymosis

;Urogenital and reproductive
*Changes in libido, impotence

ee also

* Cathinone
* Diethylcathinone
* Methcathinone
* Methylenedioxymethcathinone

References


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