SYNPO

Synaptopodin, also known as SYNPO, is a human gene.cite web | title = Entrez Gene: SYNPO synaptopodin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11346| accessdate = ]

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summary_text = Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997). [supplied by OMIM] cite web | title = Entrez Gene: SYNPO synaptopodin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11346| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, "et al." |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=
*cite journal | author=Mundel P, Heid HW, Mundel TM, "et al." |title=Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes. |journal=J. Cell Biol. |volume=139 |issue= 1 |pages= 193–204 |year= 1998 |pmid= 9314539 |doi=
*cite journal | author=Kikuno R, Nagase T, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Patrie KM, Drescher AJ, Welihinda A, "et al." |title=Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 30183–90 |year= 2002 |pmid= 12042308 |doi= 10.1074/jbc.M203072200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=He JC, Husain M, Sunamoto M, "et al." |title=Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. |journal=J. Clin. Invest. |volume=114 |issue= 5 |pages= 643–51 |year= 2004 |pmid= 15343382 |doi= 10.1172/JCI200421004
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Kremerskothen J, Plaas C, Kindler S, "et al." |title=Synaptopodin, a molecule involved in the formation of the dendritic spine apparatus, is a dual actin/alpha-actinin binding protein. |journal=J. Neurochem. |volume=92 |issue= 3 |pages= 597–606 |year= 2005 |pmid= 15659229 |doi= 10.1111/j.1471-4159.2004.02888.x
*cite journal | author=Asanuma K, Kim K, Oh J, "et al." |title=Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. |journal=J. Clin. Invest. |volume=115 |issue= 5 |pages= 1188–98 |year= 2005 |pmid= 15841212 |doi= 10.1172/JCI200523371
*cite journal | author=Husain M, D'Agati VD, He JC, "et al." |title=HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. |journal=AIDS |volume=19 |issue= 17 |pages= 1975–80 |year= 2006 |pmid= 16260903 |doi=
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Hirakawa M, Tsuruya K, Yotsueda H, "et al." |title=Expression of synaptopodin and GLEPP1 as markers of steroid responsiveness in primary focal segmental glomerulosclerosis. |journal=Life Sci. |volume=79 |issue= 8 |pages= 757–63 |year= 2006 |pmid= 16564554 |doi= 10.1016/j.lfs.2006.02.031
*cite journal | author=Asanuma K, Yanagida-Asanuma E, Faul C, "et al." |title=Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling. |journal=Nat. Cell Biol. |volume=8 |issue= 5 |pages= 485–91 |year= 2006 |pmid= 16622418 |doi= 10.1038/ncb1400
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Garovic VD, Wagner SJ, Petrovic LM, "et al." |title=Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. |journal=Nephrol. Dial. Transplant. |volume=22 |issue= 4 |pages= 1136–43 |year= 2007 |pmid= 17255128 |doi= 10.1093/ndt/gfl711

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