CHI3L1

Chitinase 3-like 1 (cartilage glycoprotein-39), also known as CHI3L1, is a human gene.cite web | title = Entrez Gene: CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1116| accessdate = ] It has been implicated in asthma, with the discovery of an allele that doubles the risk. [ [http://content.nejm.org/cgi/content/full/NEJMoa0708801v1 New England Journal of Medicine article] ]

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References

Further reading

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*cite journal | author=Rathcke CN, Vestergaard H |title=YKL-40, a new inflammatory marker with relation to insulin resistance and with a role in endothelial dysfunction and atherosclerosis. |journal=Inflamm. Res. |volume=55 |issue= 6 |pages= 221–7 |year= 2007 |pmid= 16955240 |doi= 10.1007/s00011-006-0076-y
*cite journal | author=Nyirkos P, Golds EE |title=Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period. |journal=Biochem. J. |volume=269 |issue= 1 |pages= 265–8 |year= 1990 |pmid= 2375755 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hakala BE, White C, Recklies AD |title=Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. |journal=J. Biol. Chem. |volume=268 |issue= 34 |pages= 25803–10 |year= 1994 |pmid= 8245017 |doi=
*cite journal | author=Rehli M, Krause SW, Andreesen R |title=Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation. |journal=Genomics |volume=43 |issue= 2 |pages= 221–5 |year= 1997 |pmid= 9244440 |doi= 10.1006/geno.1997.4778
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Kirkpatrick RB, Emery JG, Connor JR, "et al." |title=Induction and expression of human cartilage glycoprotein 39 in rheumatoid inflammatory and peripheral blood monocyte-derived macrophages. |journal=Exp. Cell Res. |volume=237 |issue= 1 |pages= 46–54 |year= 1998 |pmid= 9417865 |doi= 10.1006/excr.1997.3764
*cite journal | author=Renkema GH, Boot RG, Au FL, "et al." |title=Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages. |journal=Eur. J. Biochem. |volume=251 |issue= 1-2 |pages= 504–9 |year= 1998 |pmid= 9492324 |doi=
*cite journal | author=Johansen JS, Stoltenberg M, Hansen M, "et al." |title=Serum YKL-40 concentrations in patients with rheumatoid arthritis: relation to disease activity. |journal=Rheumatology (Oxford) |volume=38 |issue= 7 |pages= 618–26 |year= 1999 |pmid= 10461474 |doi=
*cite journal | author=Nordenbaek C, Johansen JS, Junker P, "et al." |title=YKL-40, a matrix protein of specific granules in neutrophils, is elevated in serum of patients with community-acquired pneumonia requiring hospitalization. |journal=J. Infect. Dis. |volume=180 |issue= 5 |pages= 1722–6 |year= 1999 |pmid= 10515841 |doi=
*cite journal | author=Connor JR, Dodds RA, Emery JG, "et al." |title=Human cartilage glycoprotein 39 (HC gp-39) mRNA expression in adult and fetal chondrocytes, osteoblasts and osteocytes by in-situ hybridization. |journal=Osteoarthr. Cartil. |volume=8 |issue= 2 |pages= 87–95 |year= 2000 |pmid= 10772238 |doi= 10.1053/joca.1999.0276
*cite journal | author=Østergaard C, Johansen JS, Benfield T, "et al." |title=YKL-40 is elevated in cerebrospinal fluid from patients with purulent meningitis. |journal=Clin. Diagn. Lab. Immunol. |volume=9 |issue= 3 |pages= 598–604 |year= 2002 |pmid= 11986266 |doi=
*cite journal | author=Kronborg G, Ostergaard C, Weis N, "et al." |title=Serum level of YKL-40 is elevated in patients with Streptococcus pneumoniae bacteremia and is associated with the outcome of the disease. |journal=Scand. J. Infect. Dis. |volume=34 |issue= 5 |pages= 323–6 |year= 2003 |pmid= 12069012 |doi=
*cite journal | author=Recklies AD, White C, Ling H |title=The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways. |journal=Biochem. J. |volume=365 |issue= Pt 1 |pages= 119–26 |year= 2002 |pmid= 12071845 |doi= 10.1042/BJ20020075
*cite journal | author=Cintin C, Johansen JS, Christensen IJ, "et al." |title=High serum YKL-40 level after surgery for colorectal carcinoma is related to short survival. |journal=Cancer |volume=95 |issue= 2 |pages= 267–74 |year= 2002 |pmid= 12124825 |doi= 10.1002/cncr.10644
*cite journal | author=Steck E, Breit S, Breusch SJ, "et al." |title=Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage. |journal=Biochem. Biophys. Res. Commun. |volume=299 |issue= 1 |pages= 109–15 |year= 2003 |pmid= 12435396 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Steenbakkers PG, Baeten D, Rovers E, "et al." |title=Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies. |journal=J. Immunol. |volume=170 |issue= 11 |pages= 5719–27 |year= 2003 |pmid= 12759455 |doi=
*cite journal | author=Houston DR, Recklies AD, Krupa JC, van Aalten DM |title=Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes. |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 30206–12 |year= 2003 |pmid= 12775711 |doi= 10.1074/jbc.M303371200
*cite journal | author=Nishikawa KC, Millis AJ |title=gp38k (CHI3L1) is a novel adhesion and migration factor for vascular cells. |journal=Exp. Cell Res. |volume=287 |issue= 1 |pages= 79–87 |year= 2003 |pmid= 12799184 |doi=

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