Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1, also known as SERPINF1, is a human gene.cite web | title = Entrez Gene: SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1| url =| accessdate = ]

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ee also

* Serpin


Further reading

citations =
*cite journal | author=Tong JP, Yao YF |title=Contribution of VEGF and PEDF to choroidal angiogenesis: a need for balanced expressions. |journal=Clin. Biochem. |volume=39 |issue= 3 |pages= 267–76 |year= 2006 |pmid= 16409998 |doi= 10.1016/j.clinbiochem.2005.11.013
*cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, "et al." |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=
*cite journal | author=Becerra SP, Sagasti A, Spinella P, Notario V |title=Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop. |journal=J. Biol. Chem. |volume=270 |issue= 43 |pages= 25992–9 |year= 1995 |pmid= 7592790 |doi=
*cite journal | author=Tombran-Tink J, Pawar H, Swaroop A, "et al." |title=Localization of the gene for pigment epithelium-derived factor (PEDF) to chromosome 17p13.1 and expression in cultured human retinoblastoma cells. |journal=Genomics |volume=19 |issue= 2 |pages= 266–72 |year= 1994 |pmid= 8188257 |doi= 10.1006/geno.1994.1057
*cite journal | author=Becerra SP, Palmer I, Kumar A, "et al." |title=Overexpression of fetal human pigment epithelium-derived factor in Escherichia coli. A functionally active neurotrophic factor. |journal=J. Biol. Chem. |volume=268 |issue= 31 |pages= 23148–56 |year= 1993 |pmid= 8226833 |doi=
*cite journal | author=Steele FR, Chader GJ, Johnson LV, Tombran-Tink J |title=Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 4 |pages= 1526–30 |year= 1993 |pmid= 8434014 |doi=
*cite journal | author=Pignolo RJ, Cristofalo VJ, Rotenberg MO |title=Senescent WI-38 cells fail to express EPC-1, a gene induced in young cells upon entry into the G0 state. |journal=J. Biol. Chem. |volume=268 |issue= 12 |pages= 8949–57 |year= 1993 |pmid= 8473338 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Ortego J, Escribano J, Becerra SP, Coca-Prados M |title=Gene expression of the neurotrophic pigment epithelium-derived factor in the human ciliary epithelium. Synthesis and secretion into the aqueous humor. |journal=Invest. Ophthalmol. Vis. Sci. |volume=37 |issue= 13 |pages= 2759–67 |year= 1997 |pmid= 8977492 |doi=
*cite journal | author=Tombran-Tink J, Mazuruk K, Rodriguez IR, "et al." |title=Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin. |journal=Mol. Vis. |volume=2 |issue= |pages= 11 |year= 1998 |pmid= 9238088 |doi=
*cite journal | author=Alberdi E, Hyde CC, Becerra SP |title=Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site. |journal=Biochemistry |volume=37 |issue= 30 |pages= 10643–52 |year= 1998 |pmid= 9692954 |doi= 10.1021/bi9802317
*cite journal | author=Dawson DW, Volpert OV, Gillis P, "et al." |title=Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. |journal=Science |volume=285 |issue= 5425 |pages= 245–8 |year= 1999 |pmid= 10398599 |doi=
*cite journal | author=Koenekoop R, Pina AL, Loyer M, "et al." |title=Four polymorphic variations in the PEDF gene identified during the mutation screening of patients with Leber congenital amaurosis. |journal=Mol. Vis. |volume=5 |issue= |pages= 10 |year= 1999 |pmid= 10398730 |doi=
*cite journal | author=Alberdi E, Aymerich MS, Becerra SP |title=Binding of pigment epithelium-derived factor (PEDF) to retinoblastoma cells and cerebellar granule neurons. Evidence for a PEDF receptor. |journal=J. Biol. Chem. |volume=274 |issue= 44 |pages= 31605–12 |year= 1999 |pmid= 10531367 |doi=
*cite journal | author=Karakousis PC, John SK, Behling KC, "et al." |title=Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues. |journal=Mol. Vis. |volume=7 |issue= |pages= 154–63 |year= 2001 |pmid= 11438800 |doi=
*cite journal | author=Simonovic M, Gettins PG, Volz K |title=Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 20 |pages= 11131–5 |year= 2001 |pmid= 11562499 |doi= 10.1073/pnas.211268598
*cite journal | author=Yamagishi S, Inagaki Y, Amano S, "et al." |title=Pigment epithelium-derived factor protects cultured retinal pericytes from advanced glycation end product-induced injury through its antioxidative properties. |journal=Biochem. Biophys. Res. Commun. |volume=296 |issue= 4 |pages= 877–82 |year= 2002 |pmid= 12200129 |doi=
*cite journal | author=Meyer C, Notari L, Becerra SP |title=Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity. |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 45400–7 |year= 2003 |pmid= 12237317 |doi= 10.1074/jbc.M208339200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Pignolo RJ, Francis MK, Rotenberg MO, Cristofalo VJ |title=Putative role for EPC-1/PEDF in the G0 growth arrest of human diploid fibroblasts. |journal=J. Cell. Physiol. |volume=195 |issue= 1 |pages= 12–20 |year= 2003 |pmid= 12599204 |doi= 10.1002/jcp.10212

External links


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