Activation-induced cytidine deaminase, also known as AICDA, is a human gene.cite web | title = Entrez Gene: AICDA activation-induced cytidine deaminase| url =| accessdate = ]

Defects are associated with Hyper-IgM syndrome type 2.

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Further reading

citations =
*cite journal | author=Wedekind JE, Dance GS, Sowden MP, Smith HC |title=Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. |journal=Trends Genet. |volume=19 |issue= 4 |pages= 207–16 |year= 2003 |pmid= 12683974 |doi=
*cite journal | author=Bransteitter R, Sneeden JL, Allen S, "et al." |title=First AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodies. |journal=J. Biol. Chem. |volume=281 |issue= 25 |pages= 16833–6 |year= 2006 |pmid= 16624806 |doi= 10.1074/jbc.R600006200
*cite journal | author=Muto T, Muramatsu M, Taniwaki M, "et al." |title=Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene. |journal=Genomics |volume=68 |issue= 1 |pages= 85–8 |year= 2001 |pmid= 10950930 |doi= 10.1006/geno.2000.6268
*cite journal | author=Revy P, Muto T, Levy Y, "et al." |title=Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). |journal=Cell |volume=102 |issue= 5 |pages= 565–75 |year= 2000 |pmid= 11007475 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Minegishi Y, Lavoie A, Cunningham-Rundles C, "et al." |title=Mutations in activation-induced cytidine deaminase in patients with hyper IgM syndrome. |journal=Clin. Immunol. |volume=97 |issue= 3 |pages= 203–10 |year= 2001 |pmid= 11112359 |doi= 10.1006/clim.2000.4956
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Noguchi E, Shibasaki M, Inudou M, "et al." |title=Association between a new polymorphism in the activation-induced cytidine deaminase gene and atopic asthma and the regulation of total serum IgE levels. |journal=J. Allergy Clin. Immunol. |volume=108 |issue= 3 |pages= 382–6 |year= 2001 |pmid= 11544457 |doi= 10.1067/mai.2001.117456
*cite journal | author=Martin A, Bardwell PD, Woo CJ, "et al." |title=Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas. |journal=Nature |volume=415 |issue= 6873 |pages= 802–6 |year= 2002 |pmid= 11823785 |doi= 10.1038/nature714
*cite journal | author=Rada C, Jarvis JM, Milstein C |title=AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 7003–8 |year= 2002 |pmid= 12011459 |doi= 10.1073/pnas.092160999
*cite journal | author=Petersen-Mahrt SK, Harris RS, Neuberger MS |title=AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. |journal=Nature |volume=418 |issue= 6893 |pages= 99–103 |year= 2002 |pmid= 12097915 |doi= 10.1038/nature00862
*cite journal | author=Dudley DD, Manis JP, Zarrin AA, "et al." |title=Internal IgH class switch region deletions are position-independent and enhanced by AID expression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 15 |pages= 9984–9 |year= 2002 |pmid= 12114543 |doi= 10.1073/pnas.152333499
*cite journal | author=Martin A, Scharff MD |title=Somatic hypermutation of the AID transgene in B and non-B cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 19 |pages= 12304–8 |year= 2002 |pmid= 12202747 |doi= 10.1073/pnas.192442899
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Greeve J, Philipsen A, Krause K, "et al." |title=Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas. |journal=Blood |volume=101 |issue= 9 |pages= 3574–80 |year= 2003 |pmid= 12511417 |doi= 10.1182/blood-2002-08-2424
*cite journal | author=Oppezzo P, Vuillier F, Vasconcelos Y, "et al." |title=Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation. |journal=Blood |volume=101 |issue= 10 |pages= 4029–32 |year= 2003 |pmid= 12521993 |doi= 10.1182/blood-2002-10-3175
*cite journal | author=Bransteitter R, Pham P, Scharff MD, Goodman MF |title=Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 7 |pages= 4102–7 |year= 2003 |pmid= 12651944 |doi= 10.1073/pnas.0730835100
*cite journal | author=Zhu Y, Nonoyama S, Morio T, "et al." |title=Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase. |journal=J. Med. Dent. Sci. |volume=50 |issue= 1 |pages= 41–6 |year= 2003 |pmid= 12715918 |doi=
*cite journal | author=Sohail A, Klapacz J, Samaranayake M, "et al." |title=Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations. |journal=Nucleic Acids Res. |volume=31 |issue= 12 |pages= 2990–4 |year= 2003 |pmid= 12799424 |doi=

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