Plastocyanin family of copper binding proteins

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Symbol = Copper-bind
Name = Copper binding proteins, plastocyanin/azurin family


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Pfam= PF00127
InterPro= IPR000923
SMART=
PROSITE = PDOC00174
SCOP = 1plc
TCDB =
OPM family= 101
OPM protein= 1sfd
PDB=PDB3|1id2C:44-132 PDB3|1t5kB:43-131 PDB3|1aaj :43-131PDB3|2racA:43-131 PDB3|1mg2O:43-131 PDB3|1mdaB:43-131PDB3|1aac :43-131 PDB3|1sfdB:43-131 PDB3|1bxaA:43-131PDB3|1sfhB:43-131 PDB3|1sf3A:43-131 PDB3|1sf5A:43-131PDB3|1aan :43-131 PDB3|2mtaA:43-131 PDB3|1tu2A:37-138PDB3|1pcs :31-126 PDB3|1jxdA:31-125 PDB3|1j5dA:31-125PDB3|1m9wA:31-126 PDB3|1j5cA:31-125 PDB3|1jxfA:31-125PDB3|1bawB:37-138 PDB3|1bxvA:37-125 PDB3|1bxuA:37-125PDB3|9pcy :1-99 PDB3|1tefB:70-168 PDB3|1ylbB:70-168PDB3|1tegA:70-168 PDB3|1ag6 :70-168 PDB3|2pcfA:70-168PDB3|1oowA:70-168 PDB3|1byoB:67-165 PDB3|1bypA:67-165PDB3|1pnc :70-168 PDB3|5pcy :70-168 PDB3|3pcy :70-168PDB3|1tkwA:70-168 PDB3|1jxgB:70-168 PDB3|1plc :70-168PDB3|4pcy :70-168 PDB3|6pcy :70-168 PDB3|2pcy :70-168PDB3|1pnd :70-168 PDB3|1pla :1-97 PDB3|1plb :1-97PDB3|2plt :49-145 PDB3|1iuz :2-98 PDB3|7pcy :2-98PDB3|1kdj :1-102 PDB3|1kdi :1-102 PDB3|1a3z :162-187PDB3|1gy2A:162-187 PDB3|1a8z :162-187 PDB3|1gy1B:162-187PDB3|1cur :162-187 PDB3|1e30B:162-187 PDB3|1rcy :162-187PDB3|2calA:162-187 PDB3|1b3iA:37-131 PDB3|2b3iA:37-131PDB3|1n3dA:73-163 PDB3|1bqr :33-121 PDB3|1zib :33-121PDB3|1bqk :33-121 PDB3|1zia :33-121 PDB3|1pzb :28-116PDB3|4paz :28-116 PDB3|1paz :28-116 PDB3|8paz :28-116PDB3|1pzc :28-116 PDB3|7paz :28-116 PDB3|1py0A:28-116PDB3|1pza :28-116 PDB3|5paz :28-116 PDB3|3paz :28-116PDB3|6paz :28-116 PDB3|1adwA:27-115 PDB3|1pmy :5-93PDB3|2azuC:21-148 PDB3|1ilsD:21-148 PDB3|2tsaB:21-148PDB3|1iluG:21-148 PDB3|1jzjB:21-148 PDB3|1jvoK:21-148PDB3|1r1cC:21-148 PDB3|1gr7C:21-148 PDB3|1e65D:21-148PDB3|1ezlB:21-148 PDB3|1xb3A:21-148 PDB3|1vlxB:21-148PDB3|3azuD:21-148 PDB3|1nzrB:21-148 PDB3|2tsbC:21-148PDB3|1xb6B:21-148 PDB3|1azrA:21-148 PDB3|1cc3B:21-148PDB3|5azuC:21-148 PDB3|1e5yD:21-148 PDB3|1i53B:23-148PDB3|5azuC:21-148 PDB3|1e5yD:21-148 PDB3|1i53B:23-148PDB3|1e67A:21-148 PDB3|1aznD:21-148 PDB3|4azuB:21-148PDB3|1jzhA:21-148 PDB3|1jzeA:21-148 PDB3|1etjC:21-148PDB3|1xb8C:21-148 PDB3|1jziB:21-148 PDB3|1e5zC:21-148PDB3|1bexB:21-148 PDB3|1ag0B:21-148 PDB3|1jzgA:21-148PDB3|1jzfA:21-148 PDB3|1jvlB:21-148 PDB3|1azu :23-148PDB3|1rkrC:1-128 PDB3|1aizA:21-148 PDB3|1a4aB:21-148PDB3|1a4bA:21-148 PDB3|1uriA:21-148 PDB3|2azaB:21-148PDB3|1a4cC:21-148 PDB3|1azbB:21-148 PDB3|1azcA:21-148PDB3|1dz0A:1-128 PDB3|1dyzA:1-128 PDB3|1nwpA:1-128PDB3|1nwoB:1-128 PDB3|1cuoA:1-128 PDB3|1uatA:1-128PDB3|1ov8A:152-234 PDB3|1qhqA:152-234

Plastocyanin/azurin family of copper binding proteins (or blue (type 1) copper domain) is a family of small proteins which bind a single copper atom and which are characterised by an intense electronic absorption band near 600 nm (see copper proteins)cite journal |author=Clingeleffer DJ, Guss JM, Rogers SJ, Freeman HC, Garrett TP |title=The crystal structure of poplar apoplastocyanin at 1.8-A resolution. The geometry of the copper-binding site is created by the polypeptide|journal=J. Biol. Chem. |volume=259 |issue=5 |pages=2822–2825 |year=1984 |pmid=6698995] cite journal |author=Hunt LT, Ryden LG |title=Evolution of protein complexity: the blue copper-containing oxidases and related proteins |journal=J. Mol. Evol. |volume=36 |issue=1 |pages=41–66 |year=1993 |pmid=8433378 |doi=10.1007/BF02407305] . The most well known members of this class of proteins are the plant chloroplastic plastocyanins, which exchange electrons with cytochrome c6, and the distantly related bacterial azurins, which exchange electrons with cytochrome c551. This family of proteins also includes amicyanin from bacteria such as "Methylobacterium extorquens" or "Paracoccus versutus" (Thiobacillus versutus) that can grow on methylamine; auracyanins A and B from "Chloroflexus aurantiacus"cite journal |author=Meyer TE, Han J, McManus JD, Brune DC, Sanders-Loehr J, Cusanovich MA, Tollin G, Blankenship RE |title=Isolation, characterization, and amino acid sequences of auracyanins, blue copper proteins from the green photosynthetic bacterium Chloroflexus aurantiacus |journal=J. Biol. Chem. |volume=267 |issue=10 |pages=6531–6540 |year=1992 |pmid=1313011] ; blue copper protein from "Alcaligenes faecalis"; cupredoxin (CPC) from "Cucumis sativus" (Cucumber) peelingscite journal |author=Messerschmidt A, Mann K, Thoenes U, Mehrabian Z, Nalbandyan R, Schafer W |title=The amino acid sequence of a type I copper protein with an unusual serine- and hydroxyproline-rich C-terminal domain isolated from cucumber peelings |journal=FEBS Lett. |volume=314 |issue=3 |pages=220–223 |year=1992 |pmid=1468551 |doi=10.1016/0014-5793(92)81475-2] ; cusacyanin (basic blue protein; plantacyanin, CBP) from cucumber; halocyanin from "Natronomonas pharaonis" (Natronobacterium pharaonis)cite journal |author=Oesterhelt D, Mattar S, Scharf B, Rodewald K, Engelhard M, Kent SB |title=The primary structure of halocyanin, an archaeal blue copper protein, predicts a lipid anchor for membrane fixation |journal=J. Biol. Chem. |volume=269 |issue=21 |pages=14939–14945 |year=1994 |pmid=8195126] , a membrane associated copper-binding protein; pseudoazurin from Pseudomonas; rusticyanin from "Thiobacillus ferrooxidans"cite journal |author=Yano T, Fukumori Y, Yamanaka T |title=The amino acid sequence of rusticyanin isolated from Thiobacillus ferrooxidans |journal=FEBS Lett. |volume=288 |issue=1 |pages=159–162 |year=1991 |pmid=1879547 |doi=10.1016/0014-5793(91)81025-4] ; stellacyanin from "Rhus vernicifera" (Japanese lacquer tree); umecyanin from the roots of "Armoracia rusticana" (Horseradish); and allergen Ra3 from ragweed. This pollen protein is evolutionary related to the above proteins, but seems to have lost the ability to bind copper. Although there is an appreciable amount of divergence in the sequences of all these proteins, the copper ligand sites are conserved.

References


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Look at other dictionaries:

  • Plastocyanin — is an important copper containing protein involved in electron transfer. The protein is monomeric, with a molecular weight around 10,500 Da, and 99 amino acids in most vascular plants. It is a member of plastocyanin family of copper binding… …   Wikipedia

  • Metalloprotein — The structure of hemoglobin. The heme cofactor, containing iron, shown in green. Metalloprotein is a generic term for a protein that contains a metal ion cofactor.[1] Metalloproteins have many different functions in cells …   Wikipedia


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