medicine, platypnea refers to shortness of breath(dyspnea) that worsens when sitting or standing up. It is the opposite of orthopnea. The word is derived from the Greek "platus" (= flat) and "pnoia" (=breath).
Platypnea is due to either
hepatopulmonary syndromeor an anatomical cardiovascular defect increasing positional right-to-left shunting (bloodflow from the right to the left part of the circulatory system). These defects include rare syndromes in which the venousblood from the liver does not pass through the lungs, or if venous blood from the portal circulationreaches the inferior vena cavawithout passing through the liver ( Abernethy malformation, type 1).
Insuficiency of abdominal muscles causes lower diafragm position and dyspnea. In clinostatism, abdominal organs push the diafragm in his normal, upper position, reducing the respiratory effort.Fact|date=May 2008
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