Y box binding protein 1

Y box binding protein 1

Y box binding protein 1, officially known as YBX1, but commonly referred to as "YB-1" by researchers, is a human protein. [cite web | title = Entrez Gene: YBX1 Y box binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4904| accessdate = ] Current research is examining its involvement in cancer, and particularly in the metastasis of cancerous cells or prevention thereof.

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Further reading

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*cite journal | author=Kolluri R, Torrey TA, Kinniburgh AJ |title=A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif. |journal=Nucleic Acids Res. |volume=20 |issue= 1 |pages= 111–6 |year= 1992 |pmid= 1738588 |doi=
*cite journal | author=Kolluri R, Kinniburgh AJ |title=Full length cDNA sequence encoding a nuclease-sensitive element DNA binding protein. |journal=Nucleic Acids Res. |volume=19 |issue= 17 |pages= 4771 |year= 1991 |pmid= 1891370 |doi=
*cite journal | author=Sakura H, Maekawa T, Imamoto F, "et al." |title=Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology. |journal=Gene |volume=73 |issue= 2 |pages= 499–507 |year= 1989 |pmid= 2977358 |doi=
*cite journal | author=Didier DK, Schiffenbauer J, Woulfe SL, "et al." |title=Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 19 |pages= 7322–6 |year= 1988 |pmid= 3174636 |doi=
*cite journal | author=Kudo S, Mattei MG, Fukuda M |title=Characterization of the gene for dbpA, a family member of the nucleic-acid-binding proteins containing a cold-shock domain. |journal=Eur. J. Biochem. |volume=231 |issue= 1 |pages= 72–82 |year= 1995 |pmid= 7628487 |doi=
*cite journal | author=Lloberas J, Maki RA, Celada A |title=Repression of major histocompatibility complex I-A beta gene expression by dbpA and dbpB (mYB-1) proteins. |journal=Mol. Cell. Biol. |volume=15 |issue= 9 |pages= 5092–9 |year= 1995 |pmid= 7651426 |doi=
*cite journal | author=Chen NN, Chang CF, Gallia GL, "et al." |title=Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 4 |pages= 1087–91 |year= 1995 |pmid= 7862639 |doi=
*cite journal | author=Horwitz EM, Maloney KA, Ley TJ |title=A human protein containing a "cold shock" domain binds specifically to H-DNA upstream from the human gamma-globin genes. |journal=J. Biol. Chem. |volume=269 |issue= 19 |pages= 14130–9 |year= 1994 |pmid= 8188694 |doi=
*cite journal | author=Kashanchi F, Duvall JF, Dittmer J, "et al." |title=Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expression. |journal=J. Virol. |volume=68 |issue= 1 |pages= 561–5 |year= 1994 |pmid= 8254772 |doi=
*cite journal | author=Makino Y, Ohga T, Toh S, "et al." |title=Structural and functional analysis of the human Y-box binding protein (YB-1) gene promoter. |journal=Nucleic Acids Res. |volume=24 |issue= 10 |pages= 1873–8 |year= 1996 |pmid= 8657568 |doi=
*cite journal | author=Funke B, Zuleger B, Benavente R, "et al." |title=The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins. |journal=Nucleic Acids Res. |volume=24 |issue= 19 |pages= 3821–8 |year= 1996 |pmid= 8871564 |doi=
*cite journal | author=Koike K, Uchiumi T, Ohga T, "et al." |title=Nuclear translocation of the Y-box binding protein by ultraviolet irradiation. |journal=FEBS Lett. |volume=417 |issue= 3 |pages= 390–4 |year= 1998 |pmid= 9409758 |doi=
*cite journal | author=Toh S, Nakamura T, Ohga T, "et al." |title=Genomic organization of the human Y-box protein (YB-1) gene. |journal=Gene |volume=206 |issue= 1 |pages= 93–7 |year= 1998 |pmid= 9461420 |doi=
*cite journal | author=Sawaya BE, Khalili K, Amini S |title=Transcription of the human immunodeficiency virus type 1 (HIV-1) promoter in central nervous system cells: effect of YB-1 on expression of the HIV-1 long terminal repeat. |journal=J. Gen. Virol. |volume=79 ( Pt 2) |issue= |pages= 239–46 |year= 1998 |pmid= 9472608 |doi=
*cite journal | author=Mertens PR, Alfonso-Jaume MA, Steinmann K, Lovett DH |title=A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription. |journal=J. Biol. Chem. |volume=273 |issue= 49 |pages= 32957–65 |year= 1999 |pmid= 9830047 |doi=
*cite journal | author=Ise T, Nagatani G, Imamura T, "et al." |title=Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen. |journal=Cancer Res. |volume=59 |issue= 2 |pages= 342–6 |year= 1999 |pmid= 9927044 |doi=
*cite journal | author=Safak M, Gallia GL, Khalili K |title=Reciprocal interaction between two cellular proteins, Puralpha and YB-1, modulates transcriptional activity of JCVCY in glial cells. |journal=Mol. Cell. Biol. |volume=19 |issue= 4 |pages= 2712–23 |year= 1999 |pmid= 10082537 |doi=
*cite journal | author=Kelm RJ, Cogan JG, Elder PK, "et al." |title=Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter. |journal=J. Biol. Chem. |volume=274 |issue= 20 |pages= 14238–45 |year= 1999 |pmid= 10318844 |doi=
*cite journal | author=Safak M, Gallia GL, Ansari SA, Khalili K |title=Physical and functional interaction between the Y-box binding protein YB-1 and human polyomavirus JC virus large T antigen. |journal=J. Virol. |volume=73 |issue= 12 |pages= 10146–57 |year= 1999 |pmid= 10559330 |doi=
*cite journal | author=Ansari SA, Safak M, Gallia GL, "et al." |title=Interaction of YB-1 with human immunodeficiency virus type 1 Tat and TAR RNA modulates viral promoter activity. |journal=J. Gen. Virol. |volume=80 ( Pt 10) |issue= |pages= 2629–38 |year= 1999 |pmid= 10573156 |doi=

External links


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