Hypertensive nephropathy Classification and external resources ICD-10 I12 ICD-9 403
Hypertensive nephropathy (or "hypertensive nephrosclerosis", or "Hypertensive renal disease") is a medical condition referring to damage to the kidney due to chronic high blood pressure.
In the kidneys, as a result of benign arterial hypertension, hyaline (pink, amorphous, homogeneous material) accumulates in the wall of small arteries and arterioles, producing the thickening of their walls and the narrowing of the lumina — hyaline arteriolosclerosis. Consequent ischemia will produce tubular atrophy, interstitial fibrosis, glomerular alterations (smaller glomeruli with different degrees of hyalinization - from mild to sclerosis of glomeruli) and periglomerular fibrosis. In advanced stages, renal failure will occur. Functional nephrons have dilated tubules, often with hyaline casts in the lumens. Additional complications often associated with hypertensive nephropathy include glomerular damage resulting in proteinuria and hematuria.
- Photo at Atlas of Pathology
- Tylicki L, Rutkowski B (2003). "[Hypertensive nephropathy: pathogenesis, diagnosis and treatment]" (in Polish). Pol. Merkur. Lekarski 14 (80): 168–73. PMID 12728683.
- Luft FC (October 2000). "Hypertensive nephrosclerosis-a cause of end-stage renal disease?". Nephrol Dial Transplant. 15 (10): 1515–7. doi:10.1093/ndt/15.10.1515. PMID 11007815. http://ndt.oxfordjournals.org/cgi/content/full/15/10/1515.
Cardiovascular disease: vascular disease · Circulatory system pathology (I70–I99, 440–456) Arteries, arterioles
Veinsprimarily lower limb (Deep vein thrombosis)abdomen (Hepatic veno-occlusive disease, Budd–Chiari syndrome, May-Thurner syndrome, Portal vein thrombosis, Renal vein thrombosis)Other Arteries or veins Blood pressure Urinary system · Pathology · Urologic disease / Uropathy (N00–N39, 580–599) AbdominalGlomerulopathy/
nephroticBy conditionType III RPG/Pauci-immuneTubulopathy/
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