NAD(P)+ transhydrogenase (AB-specific)
NAD(P)+ transhydrogenase (AB-specific) Identifiers EC number 220.127.116.11 CAS number 9014-18-0 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles
- NADPH + NAD+ NADP+ + NADH
This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is NADPH:NAD+ oxidoreductase (AB-specific). Other names in common use include pyridine nucleotide transhydrogenase, transhydrogenase, NAD(P)+ transhydrogenase, nicotinamide adenine dinucleotide (phosphate) transhydrogenase, NAD+ transhydrogenase, NADH transhydrogenase, nicotinamide nucleotide transhydrogenase, NADPH-NAD+ transhydrogenase, pyridine nucleotide transferase, NADPH-NAD+ oxidoreductase, NADH-NADP+-transhydrogenase, NADPH:NAD+ transhydrogenase, H+-Thase, energy-linked transhydrogenase, and NAD(P)+ transhydrogenase (AB-specific). This enzyme participates in nicotinate and nicotinamide metabolism.
As of late 2007, 19 structures have been solved for this class of enzymes, with PDB accession codes 1NM5, 1PNO, 1PNQ, 1PT9, 1PTJ, 1U28, 1U2D, 1U2G, 1U31, 1X13, 1X14, 1X15, 1XLT, 2BRU, 2FR8, 2FRD, 2FSV, 2OO5, and 2OOR.
- Everse, J., Anderson, B. and You, K. (Eds.), The Pyridine Nucleotide Coenzymes, The Pyridine Nucleotide Coenzymes, New York, 1982, p. 279-324.
- You KS; Oppenheimer, Norman J. (1985). "Stereospecificity for nicotinamide nucleotides in enzymatic and chemical hydride transfer reactions". CRC. Crit. Rev. Biochem. 17 (4): 313–451. doi:10.3109/10409238509113625. PMID 3157549.
This EC 1.6 enzyme-related article is a stub. You can help Wikipedia by expanding it.