IUPAC_name = 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-

C = 19 | H = 30 | O = 5
molecular_weight = 338.439 g/mol
metabolism =
elimination_half-life=18 hours
excretion =urine and feces
pregnancy_category =
legal_status =

Idebenone (pronounced eye-deb-eh-known) is an organic compound of the quinone family and promoted commercially as a synthetic analog of Coenzyme Q10 (CoQ10).

Idebenone is claimed to have properties similar to CoQ10 in its antioxidant properties.Specify|date=March 2007

Idebenone is different from Coenzyme Q10 in one very important way. During a hypoxic (low oxygen) condition, CoQ10 can switch function from an anti-oxidizing to an auto-oxidizing process. This auto-oxidation rapidly produces free radicals which damage the tissues of the body.Verify source|date=July 2007

Idebenone is said to perform the same functions as CoQ10 without the risk of an auto-oxidation reaction.Verify source|date=July 2007

Idebenone is said to promote NGF (nerve growth factor) in the brain.Verify source|date=July 2007 It appears to reduce tinnitus (ringing in the ears).Verify source|date=July 2007 Idebenone has also been used in topical applications to treat wrinkles.

Takeda Pharmaceuticals studied Idebenone which it got approved for Alzheimer's disease and Stroke.

In a one-year test on 8 patients idebenone reduced the rate of deterioration of cardiac function in patients with Friedreich's ataxia, but without halting the progression of ataxia [] .

ee also

* Free-radical theory of aging

External links

[ the website of Internaf]

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