Oxoglutarate dehydrogenase (NADP+)
oxoglutarate dehydrogenase (NADP+) Identifiers EC number 184.108.40.206 CAS number 126469-85-0 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles
- 2-oxoglutarate + CoA + NADP+ succinyl-CoA + CO2 + NADPH
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating). This enzyme is also called oxoglutarate dehydrogenase (NADP+).
- Inui H, Miyatake K, Nakano Y, Kitaoka S (Tokyo). "Occurrence of oxygen-sensitive, NADP+-dependent pyruvate dehydrogenase in mitochondria of Euglena gracilis". J. Biochem. (3): 931–4. PMID 6438078.
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