3-dehydrosphinganine reductase

In enzymology, a 3-dehydrosphinganine reductase (EC number| is an enzyme that catalyzes the chemical reaction

:sphinganine + NADP+ ightleftharpoons 3-dehydrosphinganine + NADPH + H+

Thus, the two substrates of this enzyme are sphinganine and NADP+, whereas its 3 products are 3-dehydrosphinganine, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase. Other names in common use include D-3-dehydrosphinganine reductase, D-3-oxosphinganine reductase, DSR, 3-oxosphinganine reductase, 3-oxosphinganine:NADPH oxidoreductase, and D-3-oxosphinganine:B-NADPH oxidoreductase. This enzyme participates in sphingolipid metabolism.



External links

::"The CAS registry number for this enzyme class is CAS registry|37250-36-5."

Gene Ontology (GO) codes

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Look at other dictionaries:

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

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