Tuaminoheptane

Drugbox
IUPAC_name = heptan-2-amine


CAS_number =
ATC_prefix = R01
ATC_suffix = AA11
PubChem = 5603
DrugBank =
C=7|H=17|N=1
molecular_weight = 115.217 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
legal_status =
routes_of_administration =

Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor. [Delicado EG, Fideu MD, Miras-Portugal MT, Pourrias B, Aunis D. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. "Biochemical Pharmacology". 1990 Aug 15;40(4):821-5.] However it can cause skin irritation, [Raoux M, Colomban C, Delmas P, Crest M. The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes. "Molecular Pharmacology". 2007 Jun;71(6):1685-94.] which limits its usefulness as a nasal decongestant. Side effects can include acute glaucoma, tachycardia and hypertension. [http://www.biam2.org/www/Sub2823.html]

References


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • tuaminoheptane — A sympathomimetic volatile amine, used by inhalation as a nasal decongestant; available also as t. sulfate, with the same actions, and more potent as a vasoconstrictor than ephedrine. * * * tu·am·i·no·hep·tane (too″ə …   Medical dictionary

  • tuaminoheptane sulfate — the sulfate of tuaminoheptane, having the same actions and uses as the base; applied topically to the nasal mucosa …   Medical dictionary

  • Methylhexanamine — Systematic (IUPAC) name 4 methylhexan 2 amine …   Wikipedia

  • Cathine — Not to be confused with caffeine, a compound found in coffee and tea. Cathine Systematic ( …   Wikipedia

  • Phenylpropanolamine — Systematic (IUPAC) name 2 …   Wikipedia

  • Propylhexedrine — Systematic (IUPAC) name (RS) N,α dimethyl cyclohexylethylamine …   Wikipedia

  • Cyclopentamine — Systematic (IUPAC) name (RS) 1 cyclopentyl N methyl propan 2 amine Clinical data Pregnancy cat …   Wikipedia

  • Levonordefrin — Systematic (IUPAC) name 4 [(1R,2S) 2 amino 1 hydroxypropyl]benzene 1,2 diol Clinical data Pregnancy cat …   Wikipedia

  • Norepinephrine releasing agent — Norepinephrine A norepinephrine releasing agent (NRA) is a type of drug which induces the release of norepinephrine and epinephrine from the pre synaptic neuron into the synapse. This in turn leads to increased extracellular concentrations of… …   Wikipedia

  • Amphetamine — For other uses, see Amphetamine (disambiguation). Amphetamine Systematic (IUPAC) name …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.