- Calcium channel
A Calcium channel is an
ion channelwhich displays selective permeabiltiy to calciumions. It is sometimes synonymous as voltage-dependent calcium channel, [DorlandsDict|two/000019812|calcium channel] although there are also ligand-gated calcium channels.cite journal |author=Striggow F, Ehrlich BE |title=Ligand-gated calcium channels inside and out |journal=Curr. Opin. Cell Biol. |volume=8 |issue=4 |pages=490–5 |year=1996 |month=August |pmid=8791458 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0955-0674(96)80025-1]
The following tables explain gating, gene, location and function of different types of calcium channels, both voltage and ligand-gated.
*the "receptor-operated calcium channels" (in
P2X receptorcite book |author=Walter F., PhD. Boron |title=Medical Physiology: A Cellular And Molecular Approaoch |publisher=Elsevier/Saunders |location= |year= |pages= |isbn=1-4160-2328-3 |oclc= |doi= Page 479 ]
Calcium channel blockers are used to treat hypertension.
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Look at other dictionaries:
calcium channel — Membrane channel that is specific for calcium. Probably the best characterized is the voltage gated channel of the sarcoplasmic reticulum which is ryanodine sensitive. See voltage sensitive calcium channels … Dictionary of molecular biology
calcium channel — a voltage gated channel, very permeable to calcium ions and slightly permeable to sodium ions, that upon activation by membrane depolarization allows calcium to flow into the cell; channels are classified into six subtypes (L, N, P, Q, R, and T)… … Medical dictionary
calcium channel blocker — n any of a class of drugs (as verapamil) that prevent or slow the influx of calcium ions into smooth muscle cells esp. of the heart and that are used esp. to treat some forms of angina pectoris and some cardiac arrhythmias called also calcium… … Medical dictionary
calcium channel blocker — n. any of a class of drugs, including nifedipine, diltiazem, and verapamil, that relax vascular and other smooth muscle tissue by preventing calcium ions from entering their cells, used to treat headaches, high blood pressure, angina pectoris,… … Universalium
calcium channel blocker — n. any of a class of drugs, including nifedipine, diltiazem, and verapamil, that relax vascular and other smooth muscle tissue by preventing calcium ions from entering their cells, used to treat headaches, high blood pressure, angina pectoris,… … English World dictionary
calcium-channel blocker — calcium antagonist a drug that inhibits the influx of calcium ions into cardiac and smooth muscle cells; it therefore reduces the strength of heart muscle contraction, reduces conduction of impulses in the heart, and causes vasodilatation.… … The new mediacal dictionary
Calcium channel blocker — A calcium channel blocker (CCB) is a chemical that disrupts the movement of calcium (Ca2+) through calcium channels. CCB drugs devised to target neurons are used as antiepileptics. However, the most widespread clinical usage of calcium channel … Wikipedia
calcium channel blocking agent — any of a group of drugs that inhibit the entry of calcium into cells or inhibit the mobilization of calcium from intracellular stores, resulting in slowing of atrioventricular and sinoatrial conduction and relaxation of arterial smooth and… … Medical dictionary
calcium-channel blocker — noun any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine • Syn:… … Useful english dictionary
calcium channel blocker — noun or calcium blocker : any of a class of drugs (as verapamil) that prevent or slow the influx of calcium ions into smooth muscle cells especially of the heart and that are used especially to treat some forms of angina pectoris and some cardiac … Useful english dictionary