Tacalcitol


Tacalcitol

Drugbox
IUPAC_name = (1R,3S,5Z)-5- [(2E)-2- [(1R,3aS,7aR)-1- [(2R,5R)-5-hydroxy-6-methylheptan-2-yl] -7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene] ethylidene] -4-methylidenecyclohexane-1,3-diol


CAS_number = 57333-96-7
ATC_prefix = D05
ATC_suffix = AX04
PubChem = 5283734
DrugBank =
C=27 | H=44 | O=3
molecular_weight = 416.64
bioavailability =
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metabolism =
elimination_half-life =
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pregnancy_AU =
pregnancy_US =
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routes_of_administration = Topical

Tacalcitol is a synthetic vitamin D3 analogue that is used to treat psoriasis. Tacalcitol exerts its biological activity by preventing the proliferation of keratinocytes. Tacalcitol is marketed under several names, including Curatoderm and Bonalfa.

References

* The Merck Index, 12th Edition. 9197


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