Cefixime


Cefixime
Cefixime
Systematic (IUPAC) name
(6R,7R)-7-{[2-(2-amino-1,3-thiazol-4-yl)-2-(carboxy
methoxyimino)acetyl]amino}-3-ethenyl-8-oxo-5-thia-
1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Trade names Suprax
AHFS/Drugs.com monograph
MedlinePlus a690007
Pregnancy cat. B
Legal status  ?
Routes Oral
Pharmacokinetic data
Bioavailability 40% to 50%
Protein binding Approximately 60%
Half-life Variable
Average 3 to 4 hours
Excretion Renal and biliary
Identifiers
CAS number 79350-37-1 YesY
ATC code J01DD08
PubChem CID 5362065
DrugBank APRD00583
ChemSpider 4514923 YesY
UNII 97I1C92E55 YesY
KEGG D00258 YesY
ChEBI CHEBI:472657 YesY
ChEMBL CHEMBL1541 YesY
Chemical data
Formula C16H15N5O7S2 
Mol. mass 453.452 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Cefixime is an oral third generation cephalosporin antibiotic. Cefixime is a cephalosporin antibiotic used to treat infections caused by bacteria such as pneumonia; bronchitis; gonorrhea; and ear, lung, throat, and urinary tract infections. Antibiotics will not work for colds, flu, or other viral infections.

It was sold under the trade name Suprax in the USA until 2003 when it was taken off the market by drug manufacturer Wyeth after its patent expired. The oral suspension form of "Suprax" was re-launched by Lupin in the USA.

Cefixime API is manufactured by many pharmaceutical companies the world over. The major manufacturers are based in India.


References

http://www.nlm.nih.gov/medlineplus/druginfo/meds/a690007.html


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