Gestational trophoblastic disease

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 2602
ICD10 =
ICD9 =
ICDO =
OMIM =
MedlinePlus = 001496
eMedicineSubj = med
eMedicineTopic = 866
MeshID = D031901

Gestational trophoblastic disease is any type of abnormal proliferation of trophoblasts during pregnancy. Types include:

* abnormal placenta, mostly due to abnormal fertilization
** hydatidiform mole (HM)
* frank malignant tumors of trophoblast
** invasive mole, choriocarcinoma (CCA)
** placental site trophoblastic tumor (PSTT)
** epithelioid trophoblastic tumor (ETT)
* not true neoplasms, representing abnormally formed placentas
** exaggerated placenta site (EPS)
** placental site nodule (PSN)

Treatment

Methotrexate and dactinomycin are among the chemotherapy drugs proposed for this condition. [cite journal |author=Abrão RA, de Andrade JM, Tiezzi DG, Marana HR, Dos Reis FJ, Clagnan WS |title=Treatment for low-risk gestational trophoblastic disease: Comparison of single-agent methotrexate, dactinomycin and combination regimens |journal= Gynecologic Oncology|volume= 108|issue= |pages=149|year=2007 |pmid=17931696 |doi=10.1016/j.ygyno.2007.09.006]

Molar pregnancies may be considered benign melanoma.

ee also

*Trophoblastic neoplasms

References

External links

* [http://www.paternityangel.com/Articles_zone/EarlyLoss/EarlyLoss4.htm Molar Pregnancy]
* [http://www.mymolarpregnancy.com MyMolarPregnancy.com] Information about molar pregnancy and choriocarcinoma.
* [http://www.gfmer.ch/Books/Reproductive_health/Mole.html Pathology of molar pregnancy]
* [http://www.centrontg.org EVERYTHING ABOUT MOLA, is the second highest treatment center in the world]


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Look at other dictionaries:

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  • Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… …   Medical dictionary

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  • Hydatidiform mole — Classification and external resources Histopathogic image of hydatidiform mole (complete type). H E stain. ICD 10 O …   Wikipedia


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