Special Program of Assisted Reproduction
The Special Program of Assisted Reproduction (SPAR) is a program offered to
HIVdiscordant couples ( serodiscordant) at the Bedford Research Foundation’s clinical laboratory. The program takes advantage of ART (Assisted Reproduction Technology) procedures (including " sperm washing" [cite web|url=http://americanradioworks.publicradio.org/features/evading_virus/howworks.html|title=Sperm Washing: How it Works|publisher=American Radio Works] ) to assist couples achieve a pregnancy who would otherwise risk transmitting the father's HIVinfection to the mother and the child through intercourse.
SPAR employs extremely stringent safety standards; samples will only be submitted for "
sperm washing" and cryopreservationthat have first been screened for HIV virus particlesand infected cells by specialized molecular biologytests. Only samples that have been determined to have an undetectable HIV viral burdenwill be submitted for infertilityprocedures.
Assisted Reproductive Technologies (ART), such as
In Vitro Fertilization( IVF), treat many disorders of the female, but until recent years, treatment options for male factor infertilitywere limited, and donor spermwas routinely recommended to achieve a pregnancy. Advances in ART, however, have created new possibilities for men with male factor infertility, including those whose sperm counts have been decreased by cancer treatmentand other diseases, and men with incurable, sexually transmissible virus diseases.
Infectious diseases transmissible by semen for which there is no cure include:
* Hepatitis B (and possibly Hepatitis C)
* Human T Cell Leukemia Virus (HTLV-1)
* Human Immunodeficiency Virus (HIV)
SPAR began in
1994at the New England Deaconess Hospital (now Beth Israel Deaconess Medical Center) as a support group for couples wishing to parent when one of them had an incurable sexually transmitted disease. The patient couples began raising money to fund the research needed to develop the methods to improve the safety of attempting pregnancy. By 1996sufficient funds were available to begin, but a merger between the Beth Israel Hospitaland the New England Deaconess Hospital (now Beth Israel Deaconess Medical Center) necessitated the creation of an independent Massachusetts public charity, the Assisted Reproduction Foundation (now the Bedford Stem Cell Research Foundationdirected by Dr. Ann Kiessling), to continue the work. Within two years, the methods for reducing, and perhaps eliminating, the risks of infection to the mother and the child were developed and Baby Ryan [ cite web|url=http://americanradioworks.publicradio.org/features/evading_virus/concryan.html|title=Conceiving Ryan|publisher=American Radio Works] was born in 1999.
The goal of SPAR was to provide semen testing by experts that would ensure improved safety of sperm that could then be shipped to infertility clinics near the couple's home. In this way, couples could be cared for in the same manner as other couples in their community. Fortunately, a few clinics were willing to help with this effort, and by
2002, seven collaborating clinics around the country were caring for couples living with HIVdisease.
In the Spring of
2000a ground breaking study was completed, giving significant insight to the role of semen producing organs in HIV anti-viraltherapy. [cite journal|title=HIV-1 in Semen: an isolated virus reservoir|journal= The Lancet]
* [http://www.sementesting.org Special Program of Assisted Reproduction at the Bedford Research Foundation Clinical Laboratory]
* [http://www.bedfordresearch.org Bedford Research Foundation]
Wikimedia Foundation. 2010.
Look at other dictionaries:
Bedford Stem Cell Research Foundation — ] . The institute also created the Special Program of Assisted Reproduction (SPAR), a program that assists serodiscordant couples successfully achieve pregnancy [http://www.sementesting.org/ HIV Sperm Washing | Bedford Research Foundation… … Wikipedia
Ann Kiessling — Infobox Person name = Ann Kiessling image size = 180px caption = Ann A. Kiessling, PhD birth date = birth date and age|1942|03|29 birth name = Ann Anderson birth place = death date = death place = other names = known for = Discovery of reverse… … Wikipedia
Spar (disambiguation) — A spar is a round pole of wood or metal, used on a sailing ship.Spar may also refer to:* Sparring, or practice fighting * Spar (aviation), the main structural member of the wing, running lengthways across the span of the wing * Spar (mineralogy) … Wikipedia
Serodiscordant — (sero discordant) is a term used to describe a couple in which one partner is HIV positive and the other is HIV negative. [(cite web|url=http://www.thebody.com/encyclo/couples.html |title=Couples |accessmonthday=08 26 |accessyear=2006… … Wikipedia
Sperm washing — is a term used to describe the process in which individual sperm are separated from the seminal fluid by spinning it in a centrifuge. The Sperm are then used in intrauterine insemination or in vitro fertilization. Sperm washing is a standard… … Wikipedia
Smithsonian National Zoological Park — The front entrance to the National Zoo Date opened 1889; 121 years ago (1889) … Wikipedia
Surrogacy — is an arrangement in which a woman carries and delivers a child for another couple or person. This woman may be the child s genetic mother (called traditional surrogacy), or she may carry the pregnancy to delivery after having an embryo, to which … Wikipedia
Pregnancy — For pregnancy in non human animals, see Pregnancy (mammals). Pregnancy Classification and external resources A pregnant woman at the end of the second trimester. ICD 10 … Wikipedia
Victor Babeş University of Medicine and Pharmacy, Timişoara — Infobox University name = Victor Babeş University of Medicine and Pharmacy, Timişoara Romanian Name = Universitatea de Medicină şi Farmacie Victor Babeş , Timişoara Savant/Patron = Victor Babeş motto = “A University lives by its students and its… … Wikipedia
Northwestern University School of Law — Motto Quaecumque sunt vera (Latin) Ὁ Λόγος πλήρης χάριτος καὶ ἀληθείας Ho logos pleres charitos kai aletheias (Greek) Whatsoever things are true (Philippians 4:8 AV) The word full of grace and truth ( … Wikipedia