Austin Flint murmur
cardiology, an Austin Flint murmur is a mid-diastolic, low-pitched rumbling murmurwhich is best heard at the cardiac apex. [cite journal |author=Flint A |title=On cardiac murmurs |year=1862 |journal=American Journal of the Medical Sciences, Philadelphia |volume=44 |pages=29–54] It is associated with severe aortic regurgitation, although the role of this sign in clinical practice has been questioned.cite journal |author=Babu AN, Kymes SM, Carpenter Fryer SM |title=Eponyms and the diagnosis of aortic regurgitation: what says the evidence? |journal=Ann. Intern. Med. |volume=138 |issue=9 |pages=736–42 |year=2003 |pmid=12729428 |doi=]
Echocardiography, conventional and colour flow doppler ultrasound, and cine nuclear magnetic resonance(cine NMR) imaging suggest the murmur is the result of (aortic regurgitant) flow impingement on the inner surface of the heart, i.e. the endocardium. [cite journal |author=Landzberg JS, Pflugfelder PW, Cassidy MM, Schiller NB, Higgins CB, Cheitlin MD |title=Etiology of the Austin Flint murmur |journal=J. Am. Coll. Cardiol. |volume=20 |issue=2 |pages=408–13 |year=1992 |pmid=1634679 |doi=] cite journal |author=Weir RA, Dargie HJ |title=Austin Flint Murmur |journal=N Engl J Med |volume=359 |issue=10 |pages=e11 |year=2008 |pmid=18768939 |doi= 10.1056/NEJMicm072437|url=http://content.nejm.org/cgi/content/full/359/10/e11]
Classically, it is described as being the result of
mitral valveleaftlet displacement "and" turbulent mixing of antegrademitral flow and retrogradeaortic flow: [GPnotebook|-167378943|Austin Flint murmur Accessed on: June 4, 2007.]
bloodjets from the aortic regurgitation strike the anterior leaflet of the mitral valve, which often results in premature closure of the mitral leaflets. This can be mistaken for mitral stenosis.
Turbulence of the two columns of blood: Blood from
left atriumto left ventricle and blood from aorta to left ventricle.
Aortic valve replacementmay be necessary to correct the abnormality if symptomatic.
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Austin Flint murmur — a heart murmur that is loudest in diastole and associated with a third heart sound. It is a sign of aortic regurgitation, which allows retrograde filling and rapid rise in left intraventricular pressure. This prevents the mitral valve from… … The new mediacal dictionary
Austin Flint murmur — a presystolic or mid diastolic murmur heard at the cardiac apex in aortic regurgitation, originating at the mitral valve when blood enters simultaneously from both the aorta and the left atrium … Medical dictionary
Austin Flint murmur (phenomenon) — Aus·tin Flint murmur (phenomenon) (awґstin flintґ) [Austin Flint, American physiologist, 1812â€“1886] see under murmur … Medical dictionary
Flint murmur — (flint) [Austin Flint, American physician, 1812â€“1886] see under murmur … Medical dictionary
Flint murmur — Austin Flint m … Medical dictionary
Austin Flint — Infobox Scientist name = PAGENAME box width = image size =150px caption = PAGENAME birth date = 20 October, 1812 birth place = Petersham death date = 13 March, 1886 death place = residence = citizenship = nationality = American ethnicity = field … Wikipedia
Austin Flint phenomenon — see under murmur … Medical dictionary
Flint, Austin — ▪ American physician born Oct. 20, 1812, Petersham, Mass., U.S. died March 13, 1886, New York, N.Y. one of the most eminent of 19th century physicians, and a pioneer of heart research in the United States. He discovered (1862) a disorder… … Universalium
Flint — Austin, Jr., U.S. physiologist, 1836–1915. See F. arcade. Austin, U.S. physician, 1812–1886. See Austin F. murmur, F. murmur, Austin F. phenomenon … Medical dictionary
Murmur — A Murmur is an abnormal "whooshing" sound created by blood flow through heart valves, as well as flow through chamber narrowings or unusual connections seen with congenital heart disease. It is usually heard by the doctor while… … Medical dictionary