CD52


CD52

protein
Name=CD52 molecule
caption=


width=
HGNCid=1804
Symbol=CD52
AltSymbols=CDW52
EntrezGene=1043
OMIM=114280
RefSeq=NM_001803
UniProt=P31358
PDB=
ECnumber=
Chromosome=1
Arm=p
Band=36
LocusSupplementaryData=

CD52 is a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It is a glycosylphosphatidylinositol (GPI)--anchored antigen expressed on the all lymphocytes as well as within the male genital tract.

It is the protein targeted by Alemtuzumab.

It is associated with certain types of lymphoma.cite journal |author=Piccaluga PP, Agostinelli C, Righi S, Zinzani PL, Pileri SA |title=Expression of CD52 in peripheral T-cell lymphoma |journal=Haematologica |volume=92 |issue=4 |pages=566–7 |year=2007 |pmid=17488672 |doi=]

References

External links

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