Dihydrofolic acid


Dihydrofolic acid
Dihydrofolic acid
Identifiers
CAS number 4033-27-6
PubChem 98792
ChemSpider 89228 YesY
MeSH dihydrofolate
ChEBI CHEBI:15633 YesY
ChEMBL CHEMBL46294 YesY
Jmol-3D images Image 1
Properties
Molecular formula C19H21N7O6
Molar mass 443.414 g/mol
 YesY acid (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. Since tetrahydrofolate is needed to make both purines and pyrimidines, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis. Dihydrofolic acid is also known by the name dihydrofolate - more commonly vitamin B9.

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective Wikipedia articles. [1]

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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to article go to article go to article go to article go to article start new article go to article go to article go to article go to article start new article go to article start new article go to article go to article go to article go to article go to article go to article start new article go to article go to article go to article go to article go to article Go to HMDB Go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article
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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to article go to article go to article go to article go to article start new article go to article go to article go to article go to article start new article go to article start new article go to article go to article go to article go to article go to article go to article start new article go to article go to article go to article go to article go to article Go to HMDB Go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article
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Fluorouracil (5-FU) Activity edit


References

  1. ^ The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601". http://www.wikipathways.org/index.php/Pathway:WP1601.