TGF beta receptor 1

Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) is a TGF beta receptor. TGFBR1 is its human gene.

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summary_text = The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). [cite web | title = Entrez Gene: TGFBR1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7046| accessdate = ]

ee also

* TGF beta receptors

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Massagué J |title=Receptors for the TGF-beta family. |journal=Cell |volume=69 |issue= 7 |pages= 1067–70 |year= 1992 |pmid= 1319842 |doi=
*cite journal | author=Wrana JL |title=TGF-beta receptors and signalling mechanisms. |journal=Mineral and electrolyte metabolism |volume=24 |issue= 2-3 |pages= 120–30 |year= 1998 |pmid= 9525694 |doi=
*cite journal | author=Josso N, di Clemente N, Gouédard L |title=Anti-Müllerian hormone and its receptors. |journal=Mol. Cell. Endocrinol. |volume=179 |issue= 1-2 |pages= 25–32 |year= 2001 |pmid= 11420127 |doi=

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