Nacolomab tafenatox

Nacolomab tafenatox
Nacolomab tafenatox ?
Monoclonal antibody
Type Fab fragment
Source Mouse
Target colorectal tumor antigen C242
Clinical data
Pregnancy cat.  ?
Legal status  ?
CAS number 150631-27-9 N
ATC code None
Chemical data
Formula  ?
 N(what is this?)  tafenatox (verify)

Nacolomab tafenatox is a mouse monoclonal antibody[1] designed for the treatment of colorectal cancer.[citation needed] The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).[1]

Schematic image of nacolomab tafenatox.
VH, VL: variable (antigen binding) domains of antibody fragment
CH1, CL: constant domains of antibody fragment
SAg: enterotoxin A (acting as a superantigen)

See also