Rolicyclidine

Drugbox
IUPAC_name = 1-(1-phenylcyclohexyl)pyrrolidine



width= 120
CAS_number= 2201-39-0
ATC_prefix=
ATC_suffix=
PubChem= 62436
DrugBank=
C=16 | H=23 | N=1
molecular_weight = 229.361 g/mol
bioavailability=
metabolism =
elimination_half-life=
excretion =
pregnancy_category =
legal_status = Schedule I / Class A
routes_of_administration=

Rolicyclidine (PCPy) is a dissociative anesthetic drug with hallucinogenic and sedative effects. It is similar in effects to phencyclidine but is slightly less potent and has less stimulant effects [ Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477 ] instead producing a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects. [ DEA Microgram Bulletin, 8, 143, 1975 ] Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.

ee also

*Phencyclidine
*Ketamine
*Tiletamine
*Eticyclidine
*Tenocyclidine

References


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