Levonordefrin

Levonordefrin
Systematic (IUPAC) name
4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol
Clinical data
Pregnancy cat.  ?
Legal status Prescription only
Identifiers
CAS number 829-74-3 YesY
ATC code None
PubChem CID 164739
IUPHAR ligand 508
DrugBank DB06707
ChemSpider 144416 YesY
UNII V008L6478D N
KEGG D02388 YesY
ChEMBL CHEMBL677 YesY
Chemical data
Formula C9H13NO3 
Mol. mass 183.204g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Levonordefrin (Nordefrin, Neo-Cobefrin), also known as α-methylnorepinephrine (α-Me-NE), is a sympathomimetic amine used as a topical nasal decongestant and vasoconstrictor in dentistry.[1] It is also a metabolite of the antihypertensive drug methyldopa, and plays a crucial role in its pharmacology and therapeutic benefits.

See also

  • α-Methyldopamine
  • α-Methyltyramine

References

  1. ^ Prescribing information for COOK-WAITE Carbocaine 2% with Neo-Cobefrin. Carestream Health, Inc. [1]

External links