The term chromophobe refers to histological structures which do not take up colored dye readily, and thus appear more relatively pale under the microscope -- hence their "fear" ("phobia") of "color" ("chrome").


The term is most commonly associated with the anterior pituitary, where approximately half of the cells are considered chromophobes. (Of the remaining cells, about a third are basophils, and the other two thirds acidophils.) The chromophobe cells do not actually appear clear, but rather a light blue (in contrast to the deep blue of the basophils.) [BUHistology|14002loa]


"Chromophobe" also refers to a type of renal cell carcinoma (distinct from "clear cell"). [ [ ACS :: What Is Kidney Cancer (Renal Cell Carcinoma)? ] ]


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Look at other dictionaries:

  • chromophobe — ● chromophobe adjectif Se dit de cellules qui prennent mal les colorants …   Encyclopédie Universelle

  • chromophobe — Resistant to stains, staining with difficulty or not at all; denoting certain degranulated cells in the anterior lobe of the pituitary gland. SYN: chromophobic. [chromo + G. phobos, fear] * * * chro·mo·phobe krō mə .fōb also chro·mo·pho·bic .krō… …   Medical dictionary

  • chromophobe — /kroh meuh fohb /, adj. 1. Also, chromophobic. Histol. not staining readily. n. 2. Cell Biol. a chromophobe cell in the pituitary gland. [1895 1900; CHROMO + PHOBE] * * * …   Universalium

  • chromophobe — chro•mo•phobe [[t]ˈkroʊ məˌfoʊb[/t]] also chro mo•pho′bic adj. lab not staining readily: chromophobe cells[/ex] • Etymology: 1895–1900 …   From formal English to slang

  • chromophobe — adjective Date: circa 1909 resisting staining with dyes …   New Collegiate Dictionary

  • chromophobe — noun Any cell that is resistant to staining See Also: chromophobic …   Wiktionary

  • chromophobe — adj. does not easily absorb stains, repels stains (Biology) n. cell of the pituitary gland which repels stains (Anatomy) …   English contemporary dictionary

  • chromophobe — chro·mo·phobe …   English syllables

  • chromophobe — chromophobic; adj. describing cells or tissues that do not stain well with either acidic or basic dyes. Chromophobic cells may be seen, for example, in the anterior pituitary gland. See also: adenoma …   The new mediacal dictionary

  • chromophobe — …   Useful english dictionary

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