Nevus of Ota

Nevus of Ota
Classification and external resources
ICD-10 D22.3 (ILDS D22.301)
DiseasesDB 32588
eMedicine DERM/290
MeSH D009507

Nevus of Ota (also known as "congenital melanosis bulbi,"[1] "nevus fuscoceruleus ophthalmomaxillaris," "oculodermal melanocytosis",[2]:700 and "Oculomucodermal melanocytosis"[1]) is a blue hyperpigmentation[3] that occurs on the face. It was first reported by Dr. M. T. Ota of Japan in 1939.[4]

Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of glaucoma). It should not be confused with Mongolian spot, which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among white people. Nevus of Ota may not be congenital, and may appear during puberty.


Q-switched laser has been used for treatment.[5][6]

Hydroquinone preparations are also helpful in partially treating this defect.

See also


  1. ^ a b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1720–22. ISBN 1-4160-2999-0. 
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  3. ^ Chan HH, Kono T (2003). "Nevus of Ota: clinical aspects and management". Skinmed 2 (2): 89–96; quiz 97–8. doi:10.1111/j.1540-9740.2003.01706.x. PMID 14673306.;2:89. 
  4. ^ "eMedicine - Nevi of Ota and Ito : Article by Harvey Lui". Retrieved 2008-03-22. 
  5. ^ Geronemus R. "Q-switched ruby laser therapy of nevus of Ota". Arch Dermatol. 128:1618-1622. 1992 [1]
  6. ^ Watanabe S, Takahashi H (1994). "Treatment of nevus of Ota with the Q-switched ruby laser". N. Engl. J. Med. 331 (26): 1745–50. doi:10.1056/NEJM199412293312604. PMID 7984195. 

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Look at other dictionaries:

  • Nevus de Ota — El nevus de Ota es una enfermedad cutánea y ocular que consiste en una hiperpigmentación que afecta a la piel de un sector de la cara y el ojo, siguiendo el trayecto del nervio trigémino. Está emparentada con otras alteraciones de la pigmentación …   Wikipedia Español

  • nevus of Ota — Ota nevus a persistent lesion resembling a mongolian spot, involving the conjunctiva, skin around the eye, and adjacent structures; it is seen primarily in babies and in young people around the time of puberty, and in East Asians and people of… …   Medical dictionary

  • Nevus — Clasificación y recursos externos CIE 10 I78.1 …   Wikipedia Español

  • Nevus of Ito — Classification and external resources ICD 10 D22.5 (ILDS D22.504) Nevus of Ito (also known as Nevus fuscoceruleus acromiodeltoideus ) is a cutaneous condition with similar features to the Nevus of Ota, but occurring in a different… …   Wikipedia

  • Nevus — Not to be confused with Naevius, Nevis, or Nevius. Naevus and Nevi redirect here. For the British experimental rock group, see Naevus (band). For the Eritrean footballer, see Nevi Ghebremeskez. For the Norwegian bank, see Nevi (company). Nevus… …   Wikipedia

  • nevus of Ito — a lesion similar to nevus of Ota except for its location; this type is in the region of the shoulder and upper arm in areas of distribution of the posterior supraclavicular and lateral cutaneous brachial nerves. Called also n. fuscoceruleus… …   Medical dictionary

  • Nevus — A pigmented spot on the skin, such as a mole. The plural of nevus is nevi. * * * 1. A circumscribed malformation of the skin, especially if colored by hyperpigmentation or increased vascularity; a n. may be predominantly epidermal, adnexal,… …   Medical dictionary

  • Ota nevus — (oґtah) [Masao T. Ota, Japanese dermatologist, 1885–1945] see under nevus …   Medical dictionary

  • Ota — Masao T., Japanese dermatopathologist, 1885–1945. See O. nevus. * * * ochratoxin A; occupational therapy assistant; Office of Technology Assessment; ornithine transaminase; orthotoluidine arsenite …   Medical dictionary

  • nevus fuscoceruleus ophthalmomaxillaris — n. of Ota …   Medical dictionary

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