Medullary cystic kidney disease

Medullary cystic kidney disease
Classification and external resources
ICD-9 753.16
OMIM 174000 603860
DiseasesDB 29224
MedlinePlus 000465
eMedicine ped/1393

Medullary cystic kidney disease is an autosomal dominant kidney disorder characterized by cysts in both kidneys and tubulointerstitial sclerosis leading to end-stage renal disease. The kidney disease nephronophthisis is in the classification of this disorder.

Medullary cystic kidney disease has an autosomal dominant pattern of inheritance.
  • MCKD1 has been associated with chromosome 1, but not a specific gene yet.[1]
  • MCKD2 has been associated with UMOD on chromosome 16.[2]

External Links


  1. ^ Scolari F, Viola BF, Ghiggeri GM, et al. (2003). "Towards the identification of (a) gene(s) for autosomal dominant medullary cystic kidney disease". J. Nephrol. 16 (3): 321–8. PMID 12832729. 
  2. ^ Hart TC, Gorry MC, Hart PS, et al. (December 2002). "Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy". J. Med. Genet. 39 (12): 882–92. doi:10.1136/jmg.39.12.882. PMC 1757206. PMID 12471200. 

Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Medullary cystic kidney disease, autosomal recessive type — A childhood genetic kidney disease in which there is progressive symmetrical destruction of the kidneys involving both the tubules and glomeruli, characteristically resulting in anemia, polyuria, polydipsia, isosthenuria (decreased ability to… …   Medical dictionary

  • Cystic kidney disease — Classification and external resources ICD 10 Q61 ICD 9 753.1 …   Wikipedia

  • medullary cystic disease — n a progressive familial kidney disease that is characterized by renal medullary cysts and that manifests itself in anemia and uremia * * * medullary cystic kidney disease 1. familial juvenile nephronophthisis. 2. according to some authorities,… …   Medical dictionary

  • Medullary sponge kidney — Classification and external resources Medullary sponge kidney as seen on an intravenous pyelogram ICD 10 Q …   Wikipedia

  • medullary sponge kidney — a rare congenital condition characterized by multiple small cystic dilatations of the medullary part of the renal collecting tubules, so that the organ has a spongy, porous feeling and appearance. It is usually asymptomatic, but there may be… …   Medical dictionary

  • Polycystic kidney disease — Classification and external resources Polycystic kidneys ICD 10 Q …   Wikipedia

  • Kidney cancer — Classification and external resources Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H E stain …   Wikipedia

  • Medullary carcinoma — Classification and external resources MeSH D018276 Medullary carcinoma refers to one of several tumors. The most common types are: Medullary thyroid cancer Medullary carcinoma of the breast Medullary carcinoma is a …   Wikipedia

  • Kidney — One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary… …   Medical dictionary

  • Multicystic dysplastic kidney — Classification and external resources ICD 10 Q61.4 (EUROCAT Q61.40 Q61.41) eMedicine radio/458 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.