Ichthyosis

Ichthyosis
Classification and external resources

Ichthyosis is recognized by rough, scaly skin exhibited by patients.
ICD-10 Q80
ICD-9 757.1
DiseasesDB 6646
MeSH D007057

Ichthyosis (plural ichthyoses) is a heterogeneous family of at least 28,[1] generalized, mostly genetic skin disorders. All types of ichthyosis have dry, thickened, scaly or flaky skin.[1] In many types there is cracked skin,[2] which is said to resemble the scales on a fish; the word ichthyosis comes from the Ancient Greek ιχθύς (ichthys), meaning "fish."[3] The severity of symptoms can vary enormously, from the mildest types such as ichthyosis vulgaris which may be mistaken for normal dry skin up to life-threatening conditions such as harlequin type ichthyosis. The most common type of ichthyosis is ichthyosis vulgaris, accounting for more than 95% of cases.[4]

Contents

Types

There are many types of Ichthyosis and an exact diagnosis may be difficult. Types of Ichthyosis are classified by their appearance and their genetic cause. Ichthyosis caused by the same gene can vary considerably in severity and symptoms. Some Ichthyoses don't appear to fit exactly into any one type. Also different genes can produce Ichthyoses with similar symptoms. The most common or well-known types are as follows:[5]

Genetic ichthyoses

Ichthyoses with additional characteristics

Non-genetic ichthyosis

Diagnosis

A physician often can diagnose ichthyosis by looking at the skin. A family history is very useful. In some cases, a skin biopsy is done to help to confirm the diagnosis. In a biopsy, a small piece of skin is removed and examined under a microscope. In some instances, genetic testing may be helpful in making a diagnosis. Diabetes has not been linked to acquired ichthyosis or ichthyosis vulgaris.[6]

Ichthyosis is not more or less common in any ethnic group. As of now, there is no way to prevent ichthyosis since it is often of a genetic nature.

Treatments

Treatments for ichthyosis often take the form of topical application of creams and emollient oils, in an attempt to hydrate the skin. Retinoids are also used for some conditions. Exposure to sunlight may improve or worsen the condition.

There can be ocular manifestations of ichthyosis, such as corneal and ocular surface diseases. Vascularizing keratitis, which is more commonly found in congenital keratitis-ichythosis-deafness (KID), may worsen with isotretinoin therapy.

Ichthyosis in animals

Ichthyosis or ichthyosis-like diseases exist for several types of animals, including cattle, chickens, llamas, mice, and dogs.[7] Ichthyosis of varying severity is well documented in some popular breeds of domestic dogs. The most common breeds to have ichthyosis are Golden retrievers, American bulldogs, Jack Russell terriers, and Cairn terriers.[8]

See also

References

  1. ^ a b FAQ, Foundation for Ichthyosis & Related Skin Types (F.I.R.S.T)
  2. ^ thefreedictionary.com/ichthyosis citing: Gale Encyclopedia of Medicine. Copyright 2008
  3. ^ Ichthyosis, John Hopkins Health Information Library
  4. ^ Okulicz JF, Schwartz RA (2003). "Hereditary and acquired ichthyosis vulgaris". International Journal of Dermatology 42 (2): 95–8. doi:10.1046/j.1365-4362.2003.01308.x. PMID 12708996. 
  5. ^ Types of Ichthyosis, Foundation for Ichthyosis & Related Skin Types (F.I.R.S.T)
  6. ^ Scheinfeld, N; Libkind, M; Freilich, S (2001). "New-onset ichthyosis and diabetes in a 14-year-old.". Pediatric dermatology 18 (6): 501–3. PMID 11841637. 
  7. ^ Sundberg, John P., Handbook of Mouse Mutations with Skin and Hair Abnormalities, Page 333, Published by CRC Press, 1994, ISBN 0849383722
  8. ^ Gross, Thelma Lee, Veterinary Dermatopathology, Page 174-179, Published by Blackwell Publishing, 2004, ISBN 0632064528

External links



Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Ichthyosis — Ich thy*o sis, n. [NL., fr. Gr. ichqy s fish.] (Med.) A disease in which the skin is thick, rough, and scaly; called also {fishskin}. {Ich thy*ot ic}, a. [1913 Webster] …   The Collaborative International Dictionary of English

  • ichthyosis — ichthyosis. См. ихтиозы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Ichthyōsis — (v. gr.), Fischschuppenausschlag, Hautkrankheit, wobei die Haut eine fischschuppen , bisweilen schlangenhautähnliche Entartung in Folge einer sich erzeugenden Hornsubstanz zeigt, deren höchster Grad der Stachelschweinaussatz (s.… …   Pierer's Universal-Lexikon

  • Ichthyōsis — (griech.), s. Fischschuppenkrankheit …   Meyers Großes Konversations-Lexikon

  • Ichthyosis — Ichthyōsis (grch.), Fischschuppenkrankheit, ererbte Hautkrankheit, bei der die Oberhaut mit Schüppchen und Blättchen oder bei stärkern Graden (Hystrizismus) mit dickern Hornplatten und hornigen Warzen (Krusten oder Stachelschweinmenschen) besetzt …   Kleines Konversations-Lexikon

  • Ichthyosis — Ichthyosis, griech., Fischschuppenausschlag, eine Hautkrankheit …   Herders Conversations-Lexikon

  • ichthyosis — (n.) 1815, Modern Latin, from Gk. ikhthys fish + OSIS (Cf. osis) …   Etymology dictionary

  • ichthyosis — [ik΄thē ō′sis] n. [ModL: see ICHTHY(O) & OSIS] a congenital, hereditary skin disease characterized by roughening and thickening of the horny layer of the skin, producing dryness and scaling ichthyotic [ik΄thēät′ik] adj …   English World dictionary

  • Ichthyosis — Ichthyose (altgriechisch ιχθύς, ichthýs, Fisch), synonym die international verwendete Bezeichnung Ichthyosis, ist ein Sammelbegriff für Verhornungsstörungen der Haut, die meist durch Gendefekte verursacht werden. Ichthyosen sind nicht ansteckend …   Deutsch Wikipedia

  • Ichthyosis — Dry, rectangular scales on the skin. Like fish scales. From the Greek ichthys meaning fish. Ichthyosis is not one but rather a group of skin disorders characterized by noninflammatory scaling of the skin. Many different metaphors have been used… …   Medical dictionary


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.