Phosmet


Phosmet
Phosmet[1]
Identifiers
CAS number 732-11-6 YesY
PubChem 12901
ChemSpider 12367 YesY
UNII VN04LI540Y YesY
KEGG C18756 YesY
ChEBI CHEBI:38786 YesY
ATCvet code QP53AF06,QP53BB03
Jmol-3D images Image 1
Properties
Molecular formula C11H12NO4PS2
Molar mass 317.32 g mol−1
Appearance White to off-white crystals
Density 1.03 g/cm3
Melting point

72 °C, 345 K, 162 °F

Boiling point

Decomposes at >100 °C

 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Phosmet is a phthalimide-derived, non-systemic, organophosphate insecticide used on plants and animals. It is mainly used on apple trees for control of coddling moth, though it is also used on a wide range of fruit crops, ornamentals, and vines for the control of aphids, suckers, mites, and fruit flies.[2]

Safety

Phosmet is on the US Emergency Planning List of Extremely Hazardous Substances. It is highly toxic to bees.[2]

Mark Purdey has made the controversial suggestion that phosmet may have played a key role in the epidemic of bovine spongiform encephalopathy (BSE).[3]

A 2010 study found that each 10-fold increase in urinary concentration of organophosphate metabolites was associated with a 55% to 72% increase in the odds of ADHD in children.[4]

References

  1. ^ "Phosmet Safety Card". http://www.itcilo.it/english/actrav/telearn/osh/ic/732116.htm. Retrieved 2006-08-06. 
  2. ^ a b "Toxicology of Phosmet" (Webpage). http://extoxnet.orst.edu/pips/phosmet.htm. Retrieved 2006-08-06. 
  3. ^ Purdey M (1998). "High-dose exposure to systemic phosmet insecticide modifies the phosphatidylinositol anchor on the prion protein: the origins of new variant transmissible spongiform encephalopathies?". Med. Hypotheses 50 (2): 91–111. doi:10.1016/S0306-9877(98)90194-3. PMID 9572563. 
  4. ^ http://www.medscape.com/viewarticle/721892