List of phylogenetics software


List of phylogenetics software

This list of phylogenetics software is a compilation of computational phylogenetics software used to produce phylogenetic trees. Such tools are commonly used in comparative genomics, cladistics, and bioinformatics. Methods for estimating phylogenies include neighbor-joining, maximum parsimony (also simply referred to as parsimony), UPGMA, Bayesian phylogenetic inference, maximum likelihood and distance matrix methods.

Name Description Methods Link Author
BAli-Phy Simultaneous Bayesian inference of alignment and phylogeny Bayesian inference, alignment as well as tree search. homepage M.A. Suchard, B. D. Redelings
BATWING Bayesian Analysis of Trees With Internal Node Generation Bayesian inference, demographic history, population splits download I. J. Wilson, Weale, D.Balding
BayesPhylogenies Bayesian inference of trees using Markov Chain Monte Carlo methods Bayesian inference, multiple models, mixture model (auto-partitioning) download M. Pagel, A. Meade
BayesTraits Analyses trait evolution among groups of species for which a phylogeny or sample of phylogenies is available Trait analysis download M. Pagel, A. Meade
BEAST Bayesian Evolutionary Analysis Sampling Trees Bayesian inference, relaxed molecular clock, demographic history download or development & download A. J. Drummond, A. Rambaut
Bosque Integrated graphical software to perform phylogenetic analyses, from the importing of sequences to the plotting and graphical edition of trees and alignments Distance and maximum likelihood methods (through phyml, phylip & tree-puzzle) download S. Ramirez, E. Rodriguez.
BUCKy Bayesian concordance of gene trees Bayesian concordance using modified greedy consensus of unrooted quartets stat.wisc.edu C. Ané, B. Larget, D.A. Baum, S.D. Smith, A. Rokas and B. Larget, S.K. Kotha, C.N. Dewey, C. Ané
ClustalW Progressive multiple sequence alignment Distance matrix/nearest neighbor EBI PBIL EMBNet GenomeNet Thompson et al.
fastDNAml Optimized maximum likelihood (nucleotides only) Maximum likelihood download G.J. Olsen
Geneious Geneious provides sophisticated genome and proteome research tools Neighbor-joining, UPGMA, MrBayes plugin, PHYML plugin download A. J. Drummond,M.Suchard,V.Lefort et al.
HyPhy Hypothesis testing using phylogenies Maximum likelihood, neighbor-joining, clustering techniques, distance matrices download S.L. Kosakovsky Pond, S.D.W. Frost, S.V. Muse
IQPNNI Iterative ML treesearch with stopping rule Maximum likelihood, neighbor-joining download L.S. Vinh, A. von Haeseler
LisBeth Three-item analysis for phylogenetics and biogeography Three-item analysis download J. Ducasse, N. Cao & R. Zaragüeta-Bagils
MEGA Molecular Evolutionary Genetics Analysis Distance, Parsimony and Maximum Composite Likelihood Methods download Tamura K, Dudley J, Nei M & Kumar S
Mesquite Mesquite is software for evolutionary biology, designed to help biologists analyze comparative data about organisms. Its emphasis is on phylogenetic analysis, but some of its modules concern population genetics, while others do non-phylogenetic multivariate analysis. Maximum parsimony, distance matrix, maximum likelihood Mesquite home page Wayne Maddison and D. R. Maddison
MOLPHY Molecular phylogenetics (protein or nucleotide) Maximum likelihood server J. Adachi and M. Hasegawa
MrBayes Posterior probability estimation Bayesian inference download J. Huelsenbeck, et al.
Network Free Phylogenetic Network Software Median Joining, Reduced Median, Steiner Network download A. Roehl
Nona Phylogenetic inference Maximum parsimony, implied weighting, ratchet download P. Goloboff
PAML Phylogenetic analysis by maximum likelihood Maximum likelihood and Bayesian inference download Z. Yang
PAUP* Phylogenetic analysis using parsimony (*and other methods) Maximum parsimony, distance matrix, maximum likelihood purchase D. Swofford
PHYLIP Phylogenetic inference package Maximum parsimony, distance matrix, maximum likelihood download J. Felsenstein
PhyloQuart Quartet implementation (uses sequences or distances) Quartet method download V. Berry
PyCogent Software library for genomic biology Simulating sequences, alignment, controlling third party applications, workflows, querying databases, generating graphics and phylogenetic trees documentation/download Knight et al.
QuickTree Tree construction optimized for efficiency Neighbor-joining server K. Howe, A. Bateman, R. Durbin
RAxML-HPC Randomized Axelerated Maximum Likelihood for High Performance Computing (nucleotides and aminoacids) Maximum likelihood, simple Maximum parsimony download A. Stamatakis
SEMPHY Tree reconstruction using the combined strengths of maximum-likelihood (accuracy) and neighbor-joining (speed). SEMPHY has become outdated. The authors now refer users to RAxML, which is superior in both accuracy and speed. A hybrid maximum-likelihood / neighbor-joining method SEMPHY M. Ninio, E. Privman, T. Pupko, N. Friedman
SplitsTree Tree and network program Computation, visualization and exploration of phylogenetic trees and networks SplitsTree D.H. Huson and D. Bryant
TNT Phylogenetic inference Parsimony, weighting, ratchet, tree drift, tree fusing, sectorial searches download P. Goloboff et al.
TOPALi Phylogenetic inference Phylogenetic model selection, Bayesian analysis and Maximum Likelihood phylogenetic tree estimation, detection of sites under positive selection, and recombination breakpoint location analysis Main page download Iain Milne, Dominik Lindner et al.
TreeGen Tree construction given precomputed distance data Distance matrix server ETH Zurich
TreeAlign Efficient hybrid method Distance matrix and approximate parsimony server J. Hein
Treefinder Fast ML tree reconstruction, bootstrap analysis, model selection, hypothesis testing, tree calibration, tree manipulation and visualization, computation of sitewise rates, sequence simulation, many models of evolution (DNA, protein, rRNA, mixed protein, user-definable), GUI and scripting language Maximum likelihood, distances, and others download G. Jobb
TREE-PUZZLE Maximum likelihood and statistical analysis Maximum likelihood download H.A. Schmidt, K. Strimmer, A. von Haeseler
T-REX Tree inferring and visualization, Gene transfer detection Distance, Parsimony and Maximum likelihood T-REX server V. Makarenkov, et al.
UGENE Fast and free multiplatform tree editor based Phylip 3.6 package algorithms download Unipro
Winclada GUI and tree editor (requires Nona) Maximum parsimony, ratchet download K. Nixon
Xrate Phylo-grammar engine Rate estimation, branch length estimation, alignment annotation homepage I. Holmes

See also

  • List of phylogenetic tree visualization software

External links


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