Antifibrinolytics, such as
aminocaproic acid(ε-aminocaproic acid) and tranexamic acidare used as inhibitors of fibrinolysis, which act by blocking the lysine-binding site on plasmin.
They are used in
menorrhagiaand bleeding tendency due to various causes.
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antifibrinolytic — 1. adjective Serving to inhibit fibrinolysis. 2. noun A antifibrinolytic agent … Wiktionary
antifibrinolytic — Denoting a substance that decreases the breakdown of fibrin; e.g., aminocaproic acid. * * * adj. describing an agent that inhibits the dissolution of blood clots (see fibrinolysis). Antifibrinolytic drugs include aprotinin and tranexamic acid. *… … Medical dictionary
antifibrinolytic — adj. describing an agent that inhibits the dissolution of blood clots (see fibrinolysis). Antifibrinolytic drugs include aprotinin and tranexamic acid … The new mediacal dictionary
Tranexamic acid — Systematic (IUPAC) name trans 4 (aminomethyl)cyclohexanecarboxylic acid Clinical data AHFS/ … Wikipedia
tranexamic acid — A competitive inhibitor of plasminogen activation and of plasmin; used in hemophilia to reduce or prevent hemorrhage. * * * tran·ex·am·ic acid .tran eks .am ik n an antifibrinolytic drug C8H15NO2 * * * a drug that prevents the breakdown of blood… … Medical dictionary
Medication — Medication, also referred to as medicine, can be loosely defined as any substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. [ [http://www.fda.gov/opacom/laws/fdcact/fdcact1.htm US Federal Food, Drug … Wikipedia
Fibrinolysis — is a process that prevents blood clots from growing and becoming problematic. This process has two types: primary fibrinolysis and secondary fibrinolysis. The primary type is a normal body process, whereas secondary fibrinolysis is the… … Wikipedia
Menorrhagia — ICD 10 N92.0 ICD 9 Premenopausal menorrhagia 627.0 DiseasesDB 22575 … Wikipedia
ATC code B02 — A section of the Anatomical Therapeutic Chemical Classification System.* B Blood and blood forming organs ** B02 AntihemorrhagicsB02A AntifibrinolyticsB02AA Amino acids:B02AA01 Aminocaproic acid:B02AA02 Tranexamic acid:B02AA03 Aminomethylbenzoic… … Wikipedia
Antihemorrhagic — An antihemorrhagic (antihaemorrhagic) agent is a substance that promotes hemostasis (stops bleeding). They may also be known as hemostatic (also spelled haemostatic) agents. Styptics (also spelled stiptics) are a specific type of antihemorrhagic… … Wikipedia