The term pathogenesis means step by step development of a disease due to a series of changes in the structure and /or function of a cell/tissue/organ being caused by a microbial , chemical or physical agent.The pathogenesis of a disease is the mechanism by which an etiological factor causes the disease. The term can also be used to describe the development of the disease, such as acute, chronic and recurrent. The word comes from the Greek "pathos", "disease", and "genesis", "creation".

Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown.

Most diseases are caused by multiple "pathogenetical" processes together. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression).

Often, a potential etiology is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease.

ee also

* Pathology

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Look at other dictionaries:

  • Pathogenesis — Path o*gen e*sis, n. (Med.) Pathogeny. [1913 Webster] …   The Collaborative International Dictionary of English

  • pathogenesis — (n.) 1876, from PATHO (Cf. patho ) + GENESIS (Cf. genesis) …   Etymology dictionary

  • pathogenesis — [pə thäj′ə nēpath΄ə jen′ə sis] n. [ModL: see PATHO & GENESIS] the production or development of a disease: also pathogeny [pə thäj′ə nē] pathogenetic [pə thäjə net′ik] adj …   English World dictionary

  • pathogenesis — noun Etymology: New Latin Date: 1876 the origination and development of a disease …   New Collegiate Dictionary

  • pathogenesis — n. [Gr. pathos, suffering; genesis, origin] The origination and development of disease; pathogenic adj …   Dictionary of invertebrate zoology

  • pathogenesis — pathogenetic /path oh jeuh net ik/, adj. /path euh jen euh sis/, n. the production and development of disease. Also, pathogeny /peuh thoj euh nee/. [1875 80; < NL; see PATHO , GENESIS] * * * …   Universalium

  • pathogenesis — noun a) The origin and development of a disease. b) The mechanism whereby something causes a disease. See Also: pathogen, pathogenic, pathogeny …   Wiktionary

  • Pathogenesis — The development of a disease and the chain of events leading to that disease. * * * The pathologic, physiologic, or biochemical mechanism resulting in the development of a disease or morbid process. Cf.:etiology. [patho + G. genesis, production]… …   Medical dictionary

  • pathogenesis — causation or production of disease Causation and Formation …   Phrontistery dictionary

  • pathogenesis — pæθə dÊ’enɪsɪs n. generation and development of a disease …   English contemporary dictionary

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