ImageFile = 2c-t-2.png
ImageSize = 200px
IUPACName = 2- [4-(Ethylthio)-2,5-dimethoxyphenyl] ethanamine
Section1 = Chembox Identifiers
CASNo = 207740-24-7
SMILES = NCCC1=C(OC)C=C(SCC)C(OC)=C1
Section2 = Chembox Properties
Formula = C12H19NO2S
MolarMass = 241.35 g/mol
Section3 = Chembox Hazards
2C-T-2, or 2,5-di
methoxy-4- ethyl thio phenethylamine, is a psychedelicand entheogenic phenethylamineof the 2C family. It was first synthesized in 1981by Alexander Shulgin.cite journal| last =Theobald| first =DS| coauthors =R Staack, M Puetz, HH Mauer| title =New designer drug 2,5-dimethoxy-4-ethylthio-β-phenethylamine (2C-T-2): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry| journal = Journal of Mass Spectrometry| volume =40| issue =9| pages =1157–1172| month =September | year =2005| url =| doi =10.1002/jms.890| pmid =16041763] The drug has structural and pharmacodynamic properties similar to the drugs Mescaline, MDMA(Ecstasy), and 2C-T-7.
Alexander Shulgin's book "PiHKAL (Phenethylamines i Have Known And Loved)", the dosage range is listed as 12 to 25 mg. According to Erowida threshold dose would be 5 mg, a light dose would range from 10-15 mg, a common dose is 16-32 mg and a strong dose would be considered to be 32-48 mg.
Effects are similar to the related
2C-T-7, but 2C-T-2 is said to produce more of a "body-load" and other unpleasant reactions with reported reddening of the face and warm flushes. It can also be very nauseating while coming up. However, there have been no reported deaths from 2C-T-2, unlike 2C-T-7, and the psychedelic effects have been much milder. 2C-T-2 is sometimes used as a " designer drug" as it belongs to the 2C series. The onset usually starts after about an hour of ingestion and rises for about 2 hours, then the user hits the plateau. Hallucinationssimilar to those created by LSD, psilocybin, and other serotinergic hallucinogens are very prominent on typical 2C-T-2 doses. The trip is often described as being similar to LSD due to the serotoninergic effects and hallucinations, and has some aspects similar to other phenethylamineslike MDMA(users sometimes have euphoric rushes); however, unlike MDMA, 2C-T-2 is a strong psychedelic, and its effects can be unpredictable, even for experienced users. 2C-T-2 can be just as powerful as LSD and mushrooms. Because of the particular body load of this substance, there is a larger potential for experiencing a bad tripas compared to similar hallucinogens. There are no known reports of neurotoxicitycurrently, as 2C-T-2 is a research chemical. However, it is commonly assumed that it would have the same safety level of 2C-B (since research has been done on it). Effects can last between six and eight hours.
mechanism of actionthat produces 2C-T-2’s hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a 5-HT2A serotonin receptor agonistin the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.
The toxicity of 2C-T-2 is not well documented. 2C-T-2 is considerably less potent than 2C-T-7, but it may be expected that at higher doses it would display similar toxicity to that of other phenethylamines of the
2C-Tfamily. Other phenethylaminederivatives substituted with an alkylthio group at the 4 position such as 2C-T-7and 4-MTAare known to act as selective monoamine oxidase A inhibitors, a side effect which can lead to lethal serotonin syndromewhen combined with stimulantdrugs. Most confirmed fatalities involving 2C-T drugs involve their combination with other drugs such as alcohol, MDMA(ecstasy) or cocaine. It is also dangerous for a person who takes certain kinds of medication, OTC or prescription, to ingest 2C-T-2. Unfortunately not much is known about contraindications.
After being sold under the name of Blue Mystic for some while in Dutch smartshops, the Netherlands became the first country in the world to ban 2C-T-2, and classify it as a hard drug, by law. In April, 1999, 2C-T-2 became a list I drug of the
2C-T-2 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-2 would probably be prosecuted under the
Federal Analog Actbecause of its structural similarities to 2C-T-7.
2C-T-2 and all other compounds featured in
PiHKALare illegal drugs in the United Kingdom.
* [http://www.erowid.org/library/books_online/pihkal/pihkal040.shtml PiHKAL #40 2C-T-2]
* [http://www.erowid.org/chemicals/2ct2/2ct2.shtml 2C-T-2 vault at Erowid]
** [http://www.erowid.org/chemicals/2ct7/article1/article1.shtml Sulfurous Samadhi: An Investigation of 2C-T-2 & 2C-T-7]
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