Genetic diversity

Genetic diversity

Genetic diversity is a level of biodiversity that refers to the total number of genetic characteristics in the genetic makeup of a species. It is distinguished from genetic variability, which describes the tendency of genetic characteristics to vary.

The academic field of population genetics includes several hypotheses regarding genetic diversity. The neutral theory of evolution proposes that diversity is the result of the accumulation of neutral substitutions. Diversifying selection is the hypothesis that two subpopulations of a species live in different environments that select for different alleles at a particular locus. This may occur, for instance, if a species has a large range relative to the mobility of individuals within it. Frequency-dependent selection is the hypothesis that as alleles become more common, they become less fit. This is often invoked in host-pathogen interactions, where a high frequency of a defensive allele among the host means that it is more likely that a pathogen will spread if it is able to overcome that allele.

Importance of genetic diversity

There are many different ways to measure genetic diversity. The modern causes for the loss of animal genetic diversity have also been studied and identified. [Groom, M.J., Meffe, G.K. and Carroll, C.R. (2006) "Principles of Conservation Biology (3rd ed.)". Sunderland, MA: Sinauer Associates. Website with additional information:] [Tisdell, C. (2003). Socioeconomic causes of loss of animal genetic diversity: analysis and assessment. "Ecological Economics" 45(3): 365-376.] A September 14, 2007 study conducted by the National Science Foundation found that genetic diversity and biodiversity are dependent upon each other -- that diversity within a species is necessary to maintain diversity among species, and vice versa. According to the lead researcher in the study, Dr. Richard Lankauof, "If any one type is removed from the system, the cycle can break down, and the community becomes dominated by a single species." [ Study: Loss Of Genetic Diversity Threatens Species Diversity] ]

Survival and adaptation

Genetic diversity plays a huge role in the survival and adaptability of a species. When a species’ environment changes, slight gene variations are necessary for it to adapt and survive. A species that has a large degree of genetic diversity among its individuals will have more variations from which to choose the most fitting allele. Species that have very little genetic variation are at a great risk. With very little gene variation within the species, healthy reproduction becomes increasingly difficult, and offspring often deal with similar problems to those of inbreeding. [“ Genetic Diversity." National Biological Information Infrastructure. NBII. 16 Mar. 2008]

Agricultural Relevance

When humans initially started farming, they used selective breeding to pass on desirable traits of the crops while omitting the undesirable ones. Selective breeding leads to monocultures: entire farms of nearly genetically identical plants. Little to no genetic diversity makes crops extremely susceptible to widespread disease. Bacteria morph and change constantly. When a disease causing bacteria changes to attack a specific genetic variation, it can easily wipe out vast quantities of the species. If the genetic variation that the bacterium is best at attacking happens to be that which humans have selectively bred to use for harvest, the entire crop will be wiped out. ["Introduction to Genetic Diversity." Cheetah Conservation Fund. 2002. 19 Mar. 2008]

A very similar occurrence is the cause of the infamous Potato Famine in Ireland. Since new potato plants do not come as a result of reproduction but rather from pieces of the parent plant, no genetic diversity is developed, and the entire crop is essentially a clone of one potato, it is especially susceptible to an epidemic. In the 1840s, much of Ireland’s population depended on potatoes for food. They planted namely the “lumper” variety of potato, which was susceptible to a rot-causing mold called "Phytophthora infestans". ["Monoculture and the Irish Potato Famine." Understanding Evolution. Berkley University. 19 Mar. 2008 ] This mold destroyed the vast majority of the potato crop, and left thousands of people to starve to death.

Coping with Poor Genetic Diversity

, viruses aid in the genetic shifting process. Ocean viruses, which infect the plankton, carry genes of other organisms in addition their own. When a virus containing the genes of one cell infects another, the genetic makeup of the latter changes. This constant shift of genetic make-up helps to maintain a healthy population of plankton despite complex and unpredictable environmental changes. [“Scientists Discover Interplay Between Genes and Viruses in Tiny Ocean Plankton." National Science Foundation. 23 Mar. 2006. NSF. 16 Mar. 2008]

Cheetahs are a threatened species. Extremely low genetic diversity and resulting poor sperm quality has made breeding and survivorship difficult for Cheetahs – only about 5% of cheetahs make it to adulthood. [Stephens, Tim. "Currents." University of California, Santa Cruz. 10 Aug. 1998. University of California. 19 Mar. 2008] About 10,000 years ago, all but the jubatus species of cheetahs died out. The species encountered a population bottleneck and close family relatives were forced to mate with each other, resulting in inbreeding . [" Genetic Diversity." Cheetah Conservation Fund. 2002. 19 Mar. 2008] However, it has been recently discovered that female cheetahs can mate with more than one male per litter of cubs. They undergo induced ovulation, which means that a new egg is produced every time a female mates. By mating with multiple males, the mother increases the genetic diversity within a single litter of cubs. [Fildes, Jonathan. "Cheating Cheetahs Caught by DNA." BBC News. 29 May 2007. BBC. 19 Mar. 2008 ]

Measures of Genetic Diversity

Genetic Diversity of a population can be assessed by some simple measures.

Gene Diversity is the proportion of polymorphic loci across the genome.

Heterozygosity is the mean number of individuals with polymorphic loci.

Alleles per locus is also used to demonstrate variability.

ee also

* Genetic variability
* Human Variome Project
* International HapMap Project


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