IUPAC_name = (17-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17- decahydro-6H-cyclopenta [a] phenanthren-3-yl) bis (2-chloroethyl)aminomethanoate
CAS_number = 2998-57-4
ATC_prefix = L01
ATC_suffix = XX11
PubChem = 18140
DrugBank = APRD00625
C = 23 |H = 31 |Cl = 2 |N = 1 |O = 3
molecular_weight = 440.403 g/mol
elimination_half-life = 20 hours
Estramustine (Emcyt) is a
chemotherapyagent used to treat prostate cancer. It is a derivative of estrogen(specifically, estradiol) with an nitrogen mustard- carbamateester moiety that makes it a alkylating antineoplastic agentsimilar to mechlorethamine, with estrogen-induced specificity.
Estramustine is marketed in the
United Statesby Pharmacia (now a subsidiary of Pfizer) Mechlorethamine. Estradiol.
Estramustine is indicated for the palliative treatment of metastatic and/or progressive carcinoma of the prostate.
* [http://www.pfizer.com/files/products/uspi_emcyt.pdf Emcyt prescribing information]
Wikimedia Foundation. 2010.
Look at other dictionaries:
estramustine — noun A particular drug used in chemotherapy … Wiktionary
estramustine — A combination of the hormone estradiol (an estrogen) and nitrogen mustard (an anticancer drug). Used in the palliative therapy of prostate cancer … English dictionary of cancer terms
estramustine phosphate — es·tra·mus·tine phos·phate (es″trə musґtēn) an antineoplastic agent consisting of estradiol joined to mechlorethamine (nitrogen mustard) by a carbamate link, phosphorylated to make it water soluble; administered orally for… … Medical dictionary
estramustine phosphate sodium — An antineoplastic agent that combines the actions of estrogen and nitrogen mustard in the treatment of carcinoma of the prostate … Medical dictionary
Mechlorethamine — Systematic (IUPAC) name 2 chloro N (2 chloroethyl) N methyl ethanamine Clinical data AHFS/Drugs.com … Wikipedia
Nicholas J. Vogelzang — Nicholas J. Vogelzang, M.D. Born December 13, 1949(1949 12 13) Holland, Michigan Alma mater University of Illinois School of Medicine … Wikipedia
Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… … Wikipedia
Paclitaxel — Systematic (IUPAC) name (2α,4α,5β,7β,10β,13α) 4,10 bis(acetyloxy) … Wikipedia
Methotrexate — Amethopterin redirects here. Not to be confused with aminopterin. Methotrexate Systematic ( … Wikipedia
Everolimus — Systematic (IUPAC) name dihydroxy 12 [(2R) 1 [(1S,3R,4R) 4 (2 hydroxyethoxy) 3 methoxycyclohexyl]propan 2 yl] 19,30 dimethoxy 15,17,21,23,29,35 hexamethyl 11,36 dioxa 4 azatricyclo[30.3.1.04,9]hexatriaconta 16,24,26,28 tetraene 2,3,10,14,20… … Wikipedia