Nucleus raphe pallidus
Brain: Nucleus raphe pallidus Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but 'raphe' labeled at left.) Latin nucleus raphes pallidus NeuroNames hier-738 NeuroLex ID birnlex_1375
The nucleus raphe pallidus receives afferent connections from the periaqueductal gray, the Paraventricular nucleus of hypothalamus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus.
Also, the pallidus receives afferents from the medial preoptic area, median preoptic nucleus and lateral paragigantocellular reticular nuclei .
The pallidus has recently been shown to be involved in the activation of a fever as an immunoreaction. It has been implied that the preoptic area is constantly inhibiting the raphe pallidus, especially the rostral portion, with GABA.
When the preoptic area receives immune signals from the body, the inhibition stops and the rostral portion of the raphe pallidus excites the intermediolateral cell column, which induces a fever .
The raphe pallidus has also been known to mediate the tachycardia response, an extremely high heart rate known to be incited by emotional or psychological stress.
Microinjections of a GABA-a antagonist into the raphe pallidus, induces an increased heart rate.
In both of these cases, GABA is mediating two different sympathetic responses, so clearly the nucleus raphe pallidus is a far more a complex nucleus than previously thought.
- ^ Hermann, Dirk M. et al. Afferent projections to the rat nuclei raphe magnus, raphe pallidus and reticularis gigantocellularis pars demonstrated by iontophoretic application of choleratoxin (subunit b). Journal of Chemical Neuroanatomy Volume 13, Issue 1 , June 1997, Pages 1-21
- ^ Nakamura, Kazuhiro et al. The Rostral Raphe Pallidus Nucleus Mediates Pyrogenic Transmission from the Preoptic Area. The Journal of Neuroscience, June 1, 2002, 22(11):4600-4610
- ^ Zaretsky, Dmitry V. et al. Microinjection of muscimol into raphe pallidus suppresses tachycardia associated with air stress in conscious rats. Journal of Physiology (2003), 546.1, pp. 243-250
Human brain: rhombencephalon, myelencephalon: medulla (TA A14.1.04, GA 9.767) DorsalSurfaceGrey: otherWhite: Sensory/ascendingWhite: Motor/descending VentralWhite: Motor/descendingSurface Grey: Raphe/
Wikimedia Foundation. 2010.
Look at other dictionaries:
nucleus raphes pallidus — [TA] pallidal raphe nucleus: a raphe nucleus of the medulla oblongata closely associated with the nucleus raphes obscurus; its neurons are serotoninergic … Medical dictionary
Nucleus raphe magnus — Brain: Nucleus raphe magnus Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but raphe labeled at left.) Latin nucleus raphes magnus NeuroNames … Wikipedia
Nucleus raphe obscurus — Brain: Nucleus raphe obscurus Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but raphe labeled at left.) Latin nucleus raphes obscurus NeuroNames … Wikipedia
Raphe nuclei — Infobox Brain Name = PAGENAME Latin = nuclei raphes GraySubject = GrayPage = Caption = Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but raphe labeled at left.) Caption2 = IsPartOf = Components =… … Wikipedia
Nucleus basalis of Meynert — Brain: Nucleus basalis of Meynert MRI showing a coronal plane of the head with marks showing the location of the substantia innominata, the region in which the nucleus basalis is found … Wikipedia
Nucleus accumbens — Brain: Nucleus accumbens Nucleus accumbens visible in red … Wikipedia
raphe nuclei — nuclei raphes [TA] the median column reticular nuclei, a subgroup of the reticular nuclei of the brainstem, found in narrow longitudinal sheets along the raphae of the medulla oblongata, pons, and mesencephalon; they include many neurons that… … Medical dictionary
Nucleus — 1) In cell biology, the structure that houses the chromosomes. 2) In neuroanatomy, a group of nerve cells. * * * 1. In cytology, typically a rounded or oval mass of protoplasm within the cytoplasm of a plant or animal cell; it is surrounded by a… … Medical dictionary
Nucleus ambiguus — Brain: Nucleus ambiguus Transverse section of medulla oblongata below the middle of the olive. ( Nucleus ambiguus labeled at center right.) Gray s subject #187 … Wikipedia
Nucleus prepositus hypoglossi — Located in the medulla, the nucleus prepositus hypoglossi or NPH is part of the horizontal gaze holding system. It functions as a neural integrator. A cross section of the lower pons showing the nucleus prepositus hypoglossi (#5) labeled at the… … Wikipedia