Aschoff body

Aschoff bodies or Aschoff nodules are painless nodules present in rheumatic fever.


It is an area of focal interstitial myocardial inflammation. Fully developed Aschoff bodies consist of fibrinoid change in connective tissue, lymphocytes, occasional plasma cells, and abnormal characteristic histiocytes. They are Aschoff cell granulomas with a fibrinoid necrotic centre found in the myocardium surrounding blood vessels, and other regions of the body. Myocytes in the myocardium can merge with the Aschoff cells to form giant cells of Aschoff, In addition, there are leukocytes, lymphocytes, eosinophils and plasma cells and Anitschkow myocytes.


The Aschoff bodies were discovered independently by the German pathologist Ludwig Aschoff 1904 and one year later by Paul Rudolf Geipel. [WhoNamedIt|synd|231] [K. A. L. Aschoff. Zur Myocarditisfrage. Verhandlungen der deutschen pathologischen Gesellschaft, Stuttgart, 1904, 8: 46-53. Translated in Willius & Keys, Cardiac Classics, 1941, pp. 733-739.]


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Look at other dictionaries:

  • Aschoff body — Asch·off body ä .shȯf n one of the tiny lumps in heart muscle that are typical of rheumatic heart disease and consist of swollen collagen, cells, and fibrils also one of the similar but larger lumps found under the skin esp. in rheumatic fever… …   Medical dictionary

  • aschoff body — noun or aschoff nodule ˈäˌshȯf Usage: usually capitalized A Etymology: after Ludwig Aschoff died 1942 German pathologist : one of the tiny lumps consisting of swollen collagen, cells, and fibrils found in the heart muscle and typical of… …   Useful english dictionary

  • Aschoff body — /ah shawf/, Pathol. any of the spindleshaped nodules found in heart tissue and associated with the myocarditis of rheumatic fever. Also, Aschoff nodule. [named after Ludwig Aschoff (d. 1942), German pathologist] * * * …   Universalium

  • Aschoff body — noun a painless nodule found in Rheumatic fever …   Wiktionary

  • Aschoff — n. from the medical term Aschoff body (small mass found in heart tissue) …   English contemporary dictionary

  • aschoff nodule — noun see aschoff body …   Useful english dictionary

  • body — 1. The head, neck, trunk, and extremities. The human b., consisting of head (caput), neck (collum), trunk (truncus), and limbs (membra). 2. The material part of a human, as distinguished from the …   Medical dictionary

  • Aschoff bodies (nodules) cell node — Asch·off bodies (nodules), cell, node (ahshґof) [Karl Albert Ludwig Aschoff, German pathologist, 1866–1942] see under body and cell, and see nodus atrioventricularis …   Medical dictionary

  • Aschoff — Karl Ludwig, German pathologist, 1866–1942. See A. bodies, under body, A. nodules, under nodule, node of A. and Tawara, Rokitansky A. sinuses, under sinus, A. cell …   Medical dictionary

  • Jürgen Aschoff — Jürgen Walther Ludwig Aschoff (* 25. January 1913 in Freiburg im Breisgau; † 11. October 1998 in the same city) was a German biologist and behavior physiologist; together with Erwin Bünning and Colin Pittendrigh founder of the… …   Wikipedia

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