Tiletamine is a
dissociative anestheticand pharmacologically classified as an NMDA receptor antagonist. It is related chemically and pharmacologically to other anesthetics in this family such as ketamineand phencyclidine. Tiletamine hydrochloride exists as odourless white crystals.
It is used in
veterinary medicinein the compound product "Telazol" (tiletamine/ zolazepam, 50mg/ml of each in 5ml vial) as an injectable anesthetic. It is sometimes used in combination with xylazine("Rompun") to tranquilize large mammals such as bears and horses. Telazol is the only commercially available tiletamine product in the USA.
CONTRAINDICATED in patients of an ASA statues of III or greater and in animals with CNS signs, hyperthyroidism, cardiac disease, pancreatic or renal disease, pregnancy, glaucoma, or penetrating eye injuries.
Tiletamine/zolazepam products are classified as
Schedule III controlled substances in the United States.
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