Weil-Felix test


Weil-Felix test

The Weil-Felix test is a test for the presence and type of rickettsial disease based on the agglutination of OX-strains of "Proteus vulgaris" with suspected rickettsia in a patient's blood serum. It is a heterophile agglutinition reaction. The non-motile "Proteus" strains used are OX-2, OX-19, and OX-K.

The test was developed in 1915 by bacteriologists Edmund Weil and Arthur Felix.It looks for the production of serum antibody reactive to Proteus OX19, OX2 or OxK antigens


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  • Weil-Felix test — n WEIL FELIX REACTION * * * (for typhus and certain other rickettsial diseases) the blood serum of a patient with suspected rickettsial disease is tested against certain strains of Proteus vulgaris (OX 2, OX 19, OX K).The agglutination reactions …   Medical dictionary

  • weil-felix test — noun see weil felix reaction …   Useful english dictionary

  • Weil-Felix test (reaction) — Weil Fe·lix test (reaction) (vīlґ faґliks) [Edmund Weil, Austrian physician in Czechoslovakia, 1880–1922; Arthur Felix, Polish born bacteriologist in England, 1887–1956] see under test …   Medical dictionary

  • weil-felix reaction — ˈvī(ə)lˈfāliks noun or weil felix test Usage: usually capitalized W&F Etymology: after Edmund Weil died 1922 and Arthur Felix died 1956 Austrian physicians : an agglutination test for various rickettsial infections (as typhus fever and scrub… …   Useful english dictionary

  • Weil-Felix reaction — Weil Fe·lix reaction vī(ə)l fā liks n an agglutination test for various rickettsial infections (as typhus and tsutsugamushi disease) using particular strains of bacteria of the genus Proteus that have antigens in common with the rickettsiae to be …   Medical dictionary

  • Weil-Felix reaction — a diagnostic test for typhus. A sample of the patient s serum is tested for the presence of antibodies against the organism Proteus vulgaris. Although this relatively harmless organism is not the cause of typhus, it possesses certain antigens in… …   The new mediacal dictionary

  • Weil-Felix reaction — A test for the diagnosis of typhus and certain other rickettsial diseases. In this test, the blood serum of a patient with suspected rickettsial disease is tested against certain strains of Proteus vulgaris (OX 2, OX 19, OX K). The agglutination… …   Dictionary of microbiology

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Weil — Adolf, German physician, 1848–1916. See W. disease. Edmund, Austrian physician, 1880–1922. See W. Felix reaction, W. Felix test. Ludwig A., German dentist, 1849–1895. See W. basal layer, W. basal zone …   Medical dictionary

  • Felix — Arthur, Polish bacteriologist, 1887–1956. See Weil F. reaction, Weil F. test …   Medical dictionary


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