List of recombinant proteins

Since human recombinants have replaced the animal version in human therapeutics, the prefix of "rh" for "human recombinant" appears less and less in the literature

Human recombinants that largely replaced animal or harvested from human types

*Human growth hormone (rhGH) Humatrope from Lilly and Serostim from Serono replaced cadaver harvested human growth hormone
*Human insulin (rhI) Humulin from Lilly and Novolin from Novo Nordisk among others; largely replaced bovine and porcine insulin for human therapy. Some prefer to continue using the animal-sourced preparations, as there is some evidence that synthetic insulin varieties are more likely to induce hypoglycemia unawareness. Remaining manufacturers of highly-purified animal-sourced insulin include the U.K.'s Wockhardt Ltd. (headquartered in India), Poland's Polfa Tarchomin S.A., Argentina's Laboratorios Beta S.A., and China's Wanbang Biopharma Co.
*Follicle-stimulating hormone FSH replaced Serono's Pergonal which was previously isolated from post-menopausal female urine
*Factor VIII Kogenate from Bayer replaced blood harvested factor VIII

Human recombinants with recombination as only source

*Erythropoietin (EPO) Epogen from Amgen
*Granulocyte colony-stimulating factor (G-CSF) filgrastim sold as Neupogen from Amgen; pegfilgrastim sold as Neulasta
*alpha-glactosidase A Fabrazyme by Genzyme
*alpha-L-iduronidase (rhIDU; laronidase) Aldurazyme by BioMarin Pharmaceutical and Genzyme
*N-acetylgalactosamine-4-sulfatase (rhASB; galsulfase) Naglazyme (TM) by BioMarin Pharmaceutical
*DNAse Pulmozyme by Genentech
*Tissue plasminogen activator (TPA) Activase by Genentech
*Glucocerebrosidase Ceredase by Genzyme
*Interferon (IF) Interferon-beta-1a as Avonex from Biogen Idec; Rebif from Serono; Interferon beta-1b as Betaseron from Schering
*Insulin-like growth factor 1 (IGF-1)

Animal recombinants

*Bovine somatotropin (bST)
*Porcine somatotropin (pST)
*Bovine Chymosin

Viral recombinants

*Envelope protein of the hepatitis B virus marketed as Engerix-B by SmithKline Beecham


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • List of biochemistry topics — This page aims to list articles on Wikipedia that are related to biochemistry. This is so that those interested in the subject can monitor changes to the pages by clicking on .This list is not necessarily complete or up to date if you see an… …   Wikipedia

  • List of AIDS-related topics — This is a list of AIDS related topics, many of which were originally taken from the public domain U.S. Department of Health Glossary of HIV/AIDS Related Terms, 4th Edition. [http://www.aidsinfo.nih.gov/ed resources/glossary/] NOTOC A AACTG… …   Wikipedia

  • List of Nobel laureates in Chemistry — The Nobel Prize in Chemistry was established in the 1895 will of Swedish chemist Alfred Nobel. The Nobel Prize in chemistry (Swedish: Nobelpriset i kemi) is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various… …   Wikipedia

  • List of Case Western Reserve University people — This is a list of famous individuals associated with Case Western Reserve University, including students, alumni, and faculty.Government and military* Victor Ciorbea – prime minister of Romania (1996–1997) * Bruce Cole – eighth chairman of the… …   Wikipedia

  • Nuclear magnetic resonance spectroscopy of proteins — (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins. The field was pioneered by Richard R. Ernst and Kurt Wüthrich[1], among… …   Wikipedia

  • Protein — Proteins are large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid residues. The sequence of amino acids in a protein is defined by …   Wikipedia

  • Bovine somatotropin — (abbreviated bST and BST) is a protein hormone produced in the pituitary glands of cattle. It is also called bovine growth hormone, or BGH.BST can be produced synthetically, using recombinant DNA technology. The resulting product is called… …   Wikipedia

  • Biopharmaceutical — The term biopharmacology describes a field of research closely related to pharmacokinetics, sometimes called biopharmacy. Biopharmaceuticals are medical drugs (see pharmacology) produced using biotechnology. They are proteins (including… …   Wikipedia

  • DNA vaccination — The making of a DNA vaccine. DNA vaccination is a technique for protecting an organism against disease by injecting it with genetically engineered DNA to produce an immunological response. Nucleic acid vaccines are still experimental, and have… …   Wikipedia

  • Protein purification — is a series of processes intended to isolate a single type of protein from a complex mixture. Protein purification is vital for the characterisation of the function, structure and interactions of the protein of interest. The starting material is… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.