Descemet's membrane

Descemet's membrane
Gray871.png
Vertical section of human cornea from near the margin. (Waldeyer.) Magnified.
1. Epithelium.
2. Anterior elastic lamina.
3. substantia propria.
4. Posterior elastic lamina.
(Descemet's membrane)

5. Endothelium of the anterior chamber.
a. Oblique fibers in the anterior layer of the substantia propria.
b. Lamellæ the fibers of which are cut across, producing a dotted appearance.
c. Corneal corpuscles appearing fusiform in section.
d. Lamellæ the fibers of which are cut longitudinally.
e. Transition to the sclera, with more distinct fibrillation, and surmounted by a thicker epithelium.
f. Small bloodvessels cut across near the margin of the cornea.
Latin l. limitans posterior corneae
Gray's subject #225 1008

Descemet's membrane is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea. It is composed of a different kind of collagen (Type VIII)[1] than the stroma. The endothelial layer is located at the posterior of the cornea. Descemet's membrane, as the basement membrane for the endothelial layer, is secreted by the single layer of squamous epithelial cells that compose the endothelial layer of the cornea.

Its thickness ranges from 3 μm at birth to 8-10 μm in adults.[2]

It is also known as the Posterior limiting lamina, posterior elastic lamina, lamina elastica posterior, and membrane of Demours. It was named after French physician Jean Descemet (1732–1810).

Significant damage to the membrane may require a corneal transplant as the endothelial cells depend on it for support and cannot re-grow after injury without it.[citation needed]

See also

The corneal endothelium is a single layer of squamous cells covering the surface of the cornea that faces the anterior chamber.

References

Histology A text and atlas. Michael H.Ross and Wojciech Pawlina 5th Edition 2006

  1. ^ http://emedicine.medscape.com/article/1197057-overview
  2. ^ Johnson DH, Bourne WM, Campbell RJ: The ultrastructure of Descemet's membrane. I. Changes with age in normal cornea. Arch Ophthalmol 100:1942, 1982

External links



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Look at other dictionaries:

  • Descemet’s membrane — Infobox Anatomy Name = PAGENAME Latin = l. limitans posterior corneae GraySubject = 225 GrayPage = 1008 Caption = Vertical section of human cornea from near the margin. (Waldeyer.) Magnified. 1. Epithelium. 2. Anterior elastic lamina. 3.… …   Wikipedia

  • Descemet's membrane — Des·ce·met s membrane .des( ə) .māz n a transparent highly elastic apparently structureless membrane that covers the inner surface of the cornea and is lined with endothelium called also membrane of Descemet, posterior elastic lamina Des·ce·met… …   Medical dictionary

  • Descemet's membrane — the membrane that forms the deepest layer of the stroma of the cornea of the eye. The endothelium lies between it and the aqueous humour. [Descemet (1732–1810), French anatomist] …   The new mediacal dictionary

  • descemet's membrane — (ˈ)de|sm]āz, |desə|m] noun Usage: usually capitalized D Etymology: after Jean Descemet died 1810 French anatomist : a transparent highly elastic apparently structureless membrane lined with endothelium and covering the inner surface of the cornea …   Useful english dictionary

  • membrane of Descemet — n DESCEMET S MEMBRANE …   Medical dictionary

  • membrane of descemet — Usage: usually capitalized D Etymology: after Jean Descemet died 1810 French anatomist : descemet s membrane …   Useful english dictionary

  • Membrane de Descemet — Cornée Pour les articles homonymes, voir cornée (homonymie). La cornée est la partie antérieure transparente du globe oculaire, en forme de calotte sphérique et légèrement saillante. Sommaire 1 Anatomie 2 Histologie …   Wikipédia en Français

  • Descemet Membrane Endothelial Keratoplasty — Die Descemet Membrane Endothelial Keratoplasty (DMEK) beschreibt eine spezielle Form der Hornhauttransplantation, die bei Erkrankungen der Hornhaut zum Einsatz kommt[1], die nur das Hornhautendothel betreffen. Bei solchen Erkrankungen, wie der… …   Deutsch Wikipedia

  • Descemet membrane — Des·ce·met membrane (des ə maґ) [Jean Descemet, French anatomist, 1732–1810] see lamina limitans posterior corneae …   Medical dictionary

  • Descemet stripping — removal of the posterior limiting lamina (Descemet membrane) along with the rest of the inner surface of the retina without removing other layers; see Descemet stripping endothelial keratoplasty, under keratoplasty …   Medical dictionary


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