para-Iodoamphetamine

para-Iodoamphetamine
Systematic (IUPAC) name
1-(4-iodophenyl)propan-2-amine
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 21894-72-4
ATC code  ?
PubChem CID 123870
Chemical data
Formula C9H12IN 
Mol. mass 261.103
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

para-Iodoamphetamine (PIA), also known as 4-iodoamphetamine (4-IA), is a research chemical of the phenethylamine and amphetamine chemical classes.

It acts as a selective serotonin releasing agent and is also a MAOI.[1]

4-IA is rumored to be a serotonergic neurotoxin on the account of that being reported to be the case for p-CA.

However, p-IA is a much weaker 5-HT neurotoxin than is the case for p-CA.[2]

See also

References

  1. ^ Marona-Lewicka, D; Rhee, GS; Sprague, JE; Nichols, DE (1995). "Psychostimulant-like effects of p-fluoroamphetamine in the rat". European journal of pharmacology 287 (2): 105–13. doi:10.1016/0014-2999(95)00478-5. PMID 8749023.  edit
  2. ^ Nichols, DE; Johnson, MP; Oberlender, R (1991). "5-Iodo-2-aminoindan, a nonneurotoxic analogue of p-iodoamphetamine". Pharmacology, biochemistry, and behavior 38 (1): 135–9. doi:10.1016/0091-3057(91)90601-W. PMID 1826785.  edit