Nuclear factor I

Nuclear factor I (NF-I) is a family of closely related transcription factors. They constitutively bind as dimers to specific sequences of DNA with high affinity.[1] Family members contain an unusual DNA binding domain that binds to the recognition sequence 5'-TTGGCXXXXXGCCAA-3'.[2]

Subtypes include:


  1. ^ Blomquist P, Belikov S, Wrange O (January 1999). "Increased nuclear factor 1 binding to its nucleosomal site mediated by sequence-dependent DNA structure". Nucleic Acids Res. 27 (2): 517–25. doi:10.1093/nar/27.2.517. PMC 148209. PMID 9862974. 
  2. ^ Walter F., PhD. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. pp. 125–126. ISBN 1-4160-2328-3. 

Wikimedia Foundation. 2010.

Look at other dictionaries:

  • nuclear factor I — nuclear factor I. См. ядерный фактор I. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • nuclear factor 1 — See CTF …   Dictionary of molecular biology

  • Nuclear factor of activated T-cells — NFAT NFAT pour Nuclear factor of activated T cells (facteur nucléaire des lymphocytes T activés) est un ensemble de protéines de la famille des facteurs de transcription impliquée dans la réponse immunitaire. Sommaire 1 Structure 2 Mécanisme d… …   Wikipédia en Français

  • Germ cell nuclear factor — Nuclear receptor subfamily 6, group A, member 1 Identifiers Symbols NR6A1; GCNF; GCNF1; NR61; RTR External IDs …   Wikipedia

  • Hepatocyte nuclear factor 4 alpha — Hepatocyte nuclear factor 4, alpha PDB rendering based on 1m7w …   Wikipedia

  • Hepatocyte nuclear factor 4 gamma — Hepatocyte nuclear factor 4, gamma PDB rendering based on 1lv2 …   Wikipedia

  • Hepatocyte nuclear factor 4 — protein Name=hepatocyte nuclear factor 4 alpha caption= width= HGNCid=5024 Symbol=HNF4A AltSymbols=TCF14, MODY, MODY1 EntrezGene=3172 OMIM=600281 RefSeq=NM 001030004 UniProt=P41235 PDB=1M7W ECnumber= Chromosome=20 Arm=q Band=12… …   Wikipedia

  • Hepatocyte nuclear factor-4 — Le Hepatocyte nuclear factor 4 ou HNF4 (pour facteur nucléaire hépatocytaire 4) est une protéine de la superfamille des récepteurs nucléaires, de la famille des récepteurs orphelins c est à dire un facteur de transcription ne possédant pas à ce… …   Wikipédia en Français

  • hepatocyte nuclear factor — (HNF) any of a group of transcription factors of liver specific genes involved in a variety of functions, including carcinogenesis, atherosclerosis, hyperlipidemia, insulin resistance, and hypertension …   Medical dictionary

  • Factor nuclear 4 alfa de hepatocito — Estructura tridimensional de la proteína HNF4A. HUGO …   Wikipedia Español

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.