Seproxetine

Seproxetine
Systematic (IUPAC) name
(S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Clinical data
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Oral
Pharmacokinetic data
Half-life 4-16 days
Identifiers
CAS number 126924-38-7
ATC code None
PubChem CID 4541
IUPHAR ligand 208
DrugBank DB06731
ChemSpider 4382
UNII 25CO3X0R31 YesY
Chemical data
Formula C16H16F3NO 
Mol. mass 295.30 g/mol

Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly and Company as an antidepressant but development was never completed and the drug was never marketed.

Synthesis

Seproxetine.png

Fuller, R. W.; Robertson, D. W.; Wong, D. T.; European Patent, 1990, EP 0369685 .

See also

References